Cyclic pressure induced decellularization of porcine descending aortas
Journal of Materials Science: Materials in Medicine, 2023 The demand for decellularized xenogeneic tissues used in reconstructive heart surgery has increased over the last decades. Complete decellularization of longer and tubular aortic sections suitable for clinical application has not been achieved so far ...
Barbara Messner +5 more
doaj +2 more sources
Optimized protocol for whole organ decellularization
European Journal of Medical Research, 2017 Background The idea of tissue decellularization to gain matrices for tissue engineering is promising. The aim of the present study is to establish a safe and reproducible protocol for solid tissue decellularization that prevents the architecture of the ...
A. Schmitt +8 more
doaj +3 more sources
Effect of pulsatile flow perfusion on decellularization
BioMedical Engineering OnLine, 2018 Background Decellularized animal organs have been used as scaffolds for tissue engineering. To make a properly functioning scaffolds, the extracellular matrix (ECM) components must be preserved after decellularization.
Sung Min Park +3 more
doaj +2 more sources
Development of equipment for decellularization using the perfusion method
Acta Scientiarum: Technology, 2018 This study describes the development of equipment capable of transporting decellularization fluid through an organ by perfusion to create an in vitro acellular scaffold that maintains the three-dimensional architecture of the organ.
Jonathas Haniel +5 more
doaj +2 more sources
Systematic in vitro comparison of decellularization protocols for blood vessels. [PDF]
PLoS ONE, 2018 Decellularization of native blood vessels is a promising technology to generate 3D biological scaffolds for vascular grafting. Blood vessel decellularization has been performed in previous studies under various experimental conditions, that complicates ...
Robin Simsa +7 more
doaj +2 more sources
Dextran preserves native corneal structure during decellularization [PDF]
, 2016 Corneal decellularization has become an increasingly popular technique for generating scaffolds for corneal regeneration. Most decellularization procedures result in tissue swelling, thus limiting their application.
Amy P. Lynch (7209329) +2 more
core +8 more sources
Establishment of optimal decellularization conditions using porcine placenta
Journal of Animal Reproduction and Biotechnology, 2021 Organ transplantation is currently the most fundamental treatment for organ failure, but there is a shortage of organ supply compared to those in need.
Ji Hyung Son +3 more
doaj +1 more source
Evaluation of decellularization of porcine pericardium: Decellularization of porcine pericardium [PDF]
, 2021 The porcine pericardium has been used for its great potential as a biological scaffold, produced from the extracellular matrix (ECM) and used mainly in surgeries reconstructive, tissue repair and surgical procedures for corneal reconstruction.
Santos, AJA. +4 more
core +1 more source
Decellularized Porcine Cartilage Scaffold; Validation of Decellularization and Evaluation of Biomarkers of Chondrogenesis [PDF]
International Journal of Molecular Sciences, 2021 Osteoarthritis is a major concern in the United States and worldwide. Current non-surgical and surgical approaches alleviate pain but show little evidence of cartilage restoration. Cell-based treatments may hold promise for the regeneration of hyaline cartilage-like tissue at the site of injury or wear.
Roxanne N. Stone +6 more
openaire +2 more sources
Influence of pH on Extracellular Matrix Preservation During Lung Decellularization [PDF]
, 2014 The creation of decellularized organs for use in regenerative medicine requires the preservation of the organ extracellular matrix (ECM) as a means to provide critical cues for differentiation and migration of cells that are seeded onto the organ ...
Balestrini, Jenna L. +5 more
core +1 more source