Morphological evaluation of the amniotic membrane decellularization [PDF]
, 2022 Background: Biological materials derived from decellularized tissues could be a good basis for progress in regenerative medicine while maintaining the main components of the extracellular matrix.
Ignatov, Olga +3 more
core +1 more source
A perfusion decellularization heart model - an interesting tool for cell-matrix interaction studies
Journal of Mind and Medical Sciences, 2019 Objective. In this paper, we present a technique for whole human, pig, or rat heart decellularization in order to obtain a tool for cell-matrix interaction studies and to obtain the extracellular matrix scaffold with applications to the study of cardiac ...
Mihai Meșină +4 more
doaj +1 more source
Application of decellularization-recellularization technique in plastic and reconstructive surgery
Chinese Medical Journal, 2023 . In the field of plastic and reconstructive surgery, the loss of organs or tissues caused by diseases or injuries has resulted in challenges, such as donor shortage and immunosuppression.
Yujia Shang +8 more
doaj +1 more source
Morphological evaluation of the quality of decellularized esophagus in rat
Вестник трансплантологии и искусственных органов, 2017 The main aim of our investigation was analysis and optimization of the existing protocols of esophagus decellularization in rats, identification of parameters affecting the quality of decellularization and intactness of the native properties of ...
R. Z. Nakokhov +7 more
doaj +1 more source
Development of decellularization protocol for caprine small intestine submucosa as a biomaterial
Biomaterials and Biosystems, 2022 Decellularized animal tissues have been proven to be promising biomaterials for various tissue engineering (TE) applications. Among various animal tissues, small intestine submucosa (SIS) has gained attention of many researchers due to its easy ...
Hemant Singh +5 more
doaj +1 more source
MMP9 Knockout by CRISPR-Cas9 Reduces Bladder Cancer Malignancy But Does Not Synergize With BCG and Anti-PD-L1 in an Orthotopic Mouse Model. [PDF]
IUBMB LifeABSTRACT Bladder cancer (BC) is the 10th most common cancer worldwide, accounting for approximately 5% of new cases. Several factors contribute to tumor progression, including increased MMP9. Recently, CRISPR‐Cas9 and immunotherapy have offered high specificity for treatments; therefore, we edited MMP9 using CRISPR‐Cas9 methodology to inhibit ...
Camargo JA +13 more
europepmc +2 more sources
The journey of decellularized vessel: from laboratory to operating room
Frontiers in Bioengineering and BiotechnologyOver the past few decades, there has been a remarkable advancement in the field of transplantation. But the shortage of donors is still an urgent problem that requires immediate attention.
Chenbin Kang, Hongji Yang, Hongji Yang
doaj +1 more source
Decellularized bone extracellular matrix as a promising natural substrate for bone tissue engineering [PDF]
Exploration of BioMat-XAim: The decellularization process aims to remove cellular components from the tissues while preserving the ultrastructural composition of the extracellular matrix (ECM).
Aylin Kara Özenler +2 more
doaj +1 more source
BMC Biotechnology, 2023 Background Scaffolds for tissue engineering can be received by whole organ decellularization while maintaining the site-specific extracellular matrix and the vascular tree.
Johannes Sauter +8 more
doaj +1 more source
A typical method for decellularization of plants as biomaterials
MethodsX, 2023 Decellularization is a process by which cells are removed from tissues or organs, leaving behind the extracellular matrix (ECM) structure. This process has gained interest in the fields of tissue engineering and regenerative medicine as a way to prepare ...
Melis Toker-Bayraktar +3 more
doaj +1 more source