Results 71 to 80 of about 11,220 (243)

Effects of chemical and physical methods on decellularization of murine skeletal muscles

open access: yesAnais da Academia Brasileira de Ciências, 2021
Volumetric muscle loss causes functional weakness and is often treated with muscle grafts or implant of biomaterials. Extracellular matrices, obtained through tissue decellularization, have been widely used as biological biomaterials in tissue ...
CARLA M.F.C. MIRANDA   +6 more
doaj   +1 more source

Chamber‐Specific Decellularized Extracellular Matrices Differentially Modulate Cardiomyocyte Subtypes to Drive Engineered Heart Tissue Development and Function

open access: yesAdvanced Healthcare Materials, EarlyView.
Chamber‐specific decellularized extracellular matrices (ECMs) were developed, preserving native proteomic profiles of ventricular and atrial myocardium. These innate biochemical cues differentially modulate cardiomyocyte subtypes to drive engineered heart tissue development and function, highlighting the importance of incorporating regional ECM cues in
Dong Gyu Hwang   +7 more
wiley   +1 more source

Characterization of a Decellularized Sheep Pulmonary Heart Valves and Analysis of Their Capability as a Xenograft Initial Matrix Material in Heart Valve Tissue Engineering

open access: yesBioengineering, 2023
In order to overcome the disadvantages of existing treatments in heart valve tissue engineering, decellularization studies are carried out. The main purpose of decellularization is to eliminate the immunogenicity of biologically derived grafts and to ...
Müslüm Süleyman İnal   +2 more
doaj   +1 more source

Decellularization of human umbilical arteries [PDF]

open access: yes, 2019
Arterial obstruction in small diameter (
Quiroga Garza, Alejandro   +8 more
core   +1 more source

Coaxially Electrospun Myocardial dECM‐ Based Nanofibrous Scaffolds Demonstrate Enhanced Cardiomyocyte Biocompatibility

open access: yesAdvanced Healthcare Materials, EarlyView.
Our coaxial electrospinning system is capable of incorporating decellularized myocardial extracellular matrix in a core‐sheath configuration, creating nanofibrous scaffolds. These scaffolds, in turn, support the maintenance of functional cardiomyocytes adhered to the surface of these bioactive scaffolds.
Dhanusha N. Rajapakse   +9 more
wiley   +1 more source

Representative images showing decellularization of DMSC23 cultures.

open access: yes, 2017
phase contrast (A) before and (D) after decellularization, fluorescence micrographs of DAPI staining (B) before and (E) after decellularization, and scanning electron micrographs (C) before and (F) after decellularization. Scale bar on phase contrast and
Gina D. Kusuma (816250)   +4 more
core   +1 more source

Development of a supercritical CO2 decellularization technology [PDF]

open access: yes, 2020
Decellularization of mammalian tissue describes the process by which cellular materials are removed from the extracellular matrix (ECM, Hinderer, Layland and Schenke-Layland, 2016).
Loczenski, Rabea
core  

Design and Synthesis of Peptide‐Polyester Conjugates for Cell‐Mediated Scaffold Degradation

open access: yesAdvanced Healthcare Materials, EarlyView.
This work describes polycaprolactone (PCL)‐based biomaterials engineered to degrade in response to cell‐secreted proteases. A fast‐degrading peptide (Fast) sequence is integrated into a PCL conjugate backbone to produce a biomaterial that is selectively degraded by multiple cell types compared to its scrambled control (ScrFast).
Korina Vida G. Sinad   +7 more
wiley   +1 more source

Self‐Assembled Skin Equivalents with Monoclonal CRISPR/Cas9‐Modified N/TERT‐1 Keratinocytes: A Cutting‐Edge model for Human Skin and its Diseases

open access: yesAdvanced Healthcare Materials, EarlyView.
Self‐assembled, scaffold‐free full‐thickness skin equivalents with monoclonal, genetically modified N/TERT‐1 keratinocytes represent a novel in vitro model of human skin and skin diseases. The model is highly robust, reproducible, physiologically relevant, and suitable for high‐throughput applications.
Marta Slaufova   +4 more
wiley   +1 more source

Typical example of healthy and fibrotic tissue before and after decellularization.

open access: yes, 2023
A) Fibrotic tissue before decellularization. B) Fibrotic tissue after decellularization (SDS). C) Healthy tissue before decellularization. D) Healthy tissue after decellularization (SDS). (PDF)
Laetitia M. O. de Kort (11529873)   +7 more
core   +1 more source

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