Results 51 to 60 of about 48,259 (241)

Trained Memory of Uterine Macrophages Improves Subsequent Pregnancy Outcomes

Advanced Science, EarlyView.
This study identifies that pregnancy imprints a durable, pregnancy‐specific form of trained immune memory in uterine macrophages, marked by the emergence of LILRB3+/PIR‐B+ cells that expand across gestations, acquire a tolerogenic and metabolically rewired phenotype, and actively protect against inflammatory pregnancy loss in mice.
Jing Wang, Ning Lu, Xin‐Xiu Lin, Xu‐Hui Fang, Yi‐Hui Li, Qing‐Peng Luo, Yu‐Ting Peng, Gil Mor, Ai‐Hua Liao   +8 more
wiley   +1 more source

Myeloid Derived Suppressor Cells Interactions With Natural Killer Cells and Pro-angiogenic Activities: Roles in Tumor Progression

Frontiers in Immunology, 2019
Myeloid-derived suppressor cells (MDSCs) contribute to the induction of an immune suppressive/anergic, tumor permissive environment. MDSCs act as immunosuppression orchestrators also by interacting with several components of both innate and adaptive ...
Antonino Bruno, Lorenzo Mortara, Denisa Baci, Douglas M. Noonan, Douglas M. Noonan, Adriana Albini, Adriana Albini   +6 more
doaj   +1 more source

Adhesive and degradative properties of human placental cytotrophoblast cells in vitro. [PDF]

, 1989
Human fetal development depends on the embryo rapidly gaining access to the maternal circulation. The trophoblast cells that form the fetal portion of the human placenta have solved this problem by transiently exhibiting certain tumor-like properties ...
Cui, TY, Damsky, CH, Fisher, SJ, Grahl, K, Hartman, L, Tarpey, J, Zhang, GY, Zhang, L   +7 more
core   +3 more sources

Placental crises: disruptive selection and maternal under‐investment as the foundations of mammalian placental evolution and dysfunction

Biological Reviews, EarlyView.
ABSTRACT Among the vertebrates, mammals are notable for the dominance of live birth and placental nutrition. The structural diversity of the mammalian placenta is remarkable, despite sharing a single common ancestor and conserved physiological functions.
Davis Laundon, Neil J. Gostling, Ian G. Reddin, Bram G. Sengers, Pascale Chavatte‐Palmer, Rohan M. Lewis   +5 more
wiley   +1 more source

Term and Preterm Birth Initiation Is Associated with the Macrophages Shifting to M1 Polarization in Gestational Tissues in Mice

Biology, 2022
Inflammation in gestational tissues plays critical role in parturition initiation. We sought to investigate the leukocyte infiltration and cytokine profile in uterine tissues to understand the inflammation during term and preterm labor in the mouse model.
Yali Shan, Shiping Shen, Jing Long, Zhengshan Tang, Cichun Wu, Xin Ni   +5 more
doaj   +1 more source

Estrone and estradiol concentrations in human ovaries, testes, and adrenals during the first two years of life [PDF]

, 1987
To determine the origin of estrogens in infant blood, we measured estrone (E1) and estradiol (E2) in the gonads of 50 girls and 64 boys who died suddenly between birth and 2 yr of age as well as in the adrenals of 18 of these infant girls and 16 of the ...
Bidlingmaier, F., Dorr, H. G., Eisenmenger, Wolfgang, Knorr, D., Strom, T. M.   +4 more
core   +1 more source

Pre‐industrial land‐use limits contemporary shrub encroachment in the French Alps

Ecography, EarlyView.
Shrub encroachment has become a global phenomenon in recent decades. While global warming in the Arctic is often cited as the primary cause, human‐managed mountain regions have experienced intense historical land‐use that may also play a considerable role.
Baptiste Nicoud, Florian Carrière, Arthur Bayle, Christian Devlieger, Philippe Choler, Christophe Corona, Sandra Lavorel   +6 more
wiley   +1 more source

Expression of Estrogen Receptor α by Decidual Macrophages in Preeclampsia

Biomedicines, 2021
Preeclampsia is a gestation-associated hypertensive syndrome that threatens the life and health of the mother and the child. The condition is presumably caused by systemic failure with a strong involvement of innate immunity.
Polina Vishnyakova, Anastasiya Poltavets, Maria Nikitina, Konstantin Midiber, Liudmila Mikhaleva, Kamilla Muminova, Alena Potapova, Zulfiya Khodzhaeva, Alexey Pyregov, Andrey Elchaninov, Timur Fatkhudinov, Gennady Sukhikh   +11 more
doaj   +1 more source

Total cervical occlusion: A solution after cervico‐isthmic cerclage failure

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Spontaneous preterm birth is mainly caused by cervical incompetence. Cervical cerclage is the gold standard for preventing mid‐trimester losses and preterm deliveries. If cervical cerclage fails, cervico‐isthmic cerclage may be indicated.
Déborah Couet, Anne‐Gaëlle Pourcelot, Claire Szmulevicz, Perrine Capmas, Hervé Fernandez, Élodie Debras   +5 more
wiley   +1 more source

Deciphering decidual leukocyte traffic with serial intravascular staining

Frontiers in Immunology
The decidual immunome is dynamic, dramatically changing its composition across gestation. Early pregnancy is dominated by decidual NK cells, with a shift towards T cells later in pregnancy.
Jessica Vazquez, Jessica Vazquez, Mona A. Mohamed, Soma Banerjee, Logan T. Keding, Logan T. Keding, Michelle R. Koenig, Fernanda Leyva Jaimes, Fernanda Leyva Jaimes, Rachel C. Fisher, Emily M. Bove, Thaddeus G. Golos, Thaddeus G. Golos, Thaddeus G. Golos, Aleksandar K. Stanic   +14 more
doaj   +1 more source