Results 181 to 190 of about 1,667,357 (297)

Dialogue Model Using Arguments for Consensus Decision Making Through Common Knowledge Formation

open access: diamond, 2019
Ayslan Trevizan Possebom   +2 more
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

The role of attention in multi attribute decision making. [PDF]

open access: yesNat Commun
Sampson AL   +5 more
europepmc   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

The role of abdominal ultrasound in surgical decision making for necrotizing enterocolitis. [PDF]

open access: yesJ Neonatal Perinatal Med
Garg PM   +4 more
europepmc   +1 more source

Risk management improvement drivers for effective risk-based decision-making

open access: diamond, 2019
Fernando Vegas-Fernández   +1 more
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

HOPE or Overreach? Ethical Gaps in ECPR Decision-Making for the Nonagenarian. [PDF]

open access: yesScand J Trauma Resusc Emerg Med
Schöchl H, Schnöll B, Gratz J.
europepmc   +1 more source

Home - About - Disclaimer - Privacy