Results 101 to 110 of about 12,247,021 (294)

Chapter 7 Aging, Memory, and Decision Making

open access: yes, 2015
Aging differentially affects diverse aspects of memory functioning. In turn, memory changes have specific effects on different judgment and decision-making tasks.
Nilsson, L-G   +2 more
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Can asymmetric subjective opportunity cost effect explain impatience in intertemporal choice? A replication study

open access: yes, 2019
In "The value of nothing: asymmetric attention to opportunity costs drives intertemporal decision making" Read, Olivola and Hardisty (2017) proposed an asymmetric subjective opportunity cost (ASOC) effect to explain and predict why impatience can be ...
Huang, Yuan-Na   +3 more
core   +3 more sources

Prediction models for COVID-19 clinical decision making

open access: yesThe Lancet: Digital Health, 2020
Artuur M Leeuwenberg, Ewoud Schuit
doaj   +1 more source

Applying Generative Artificial Intelligence to cognitive models of decision making

open access: yesFrontiers in Psychology
IntroductionGenerative Artificial Intelligence has made significant impacts in many fields, including computational cognitive modeling of decision making, although these applications have not yet been theoretically related to each other.
Tyler Malloy, Cleotilde Gonzalez
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

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