Results 201 to 210 of about 12,247,021 (294)

Large Language Models in Multidisciplinary Decision-Making for Hepatopancreatobiliary Oncology: Retrospective Comparative Feasibility Study. [PDF]

J Med Internet Res
Jo SJ, Chong EH, Kang I, Yang SJ, Kang B, Kim JS, Chon HJ, Kwon CI, Sung MJ, Shin SP, An C, Lim HY, Yu JS, Jang S, Im JH, Ko KH, Lee SH.   +16 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Logical Models of Group Decision Making, 12–16 August

The Reasoner, 2013
Francesca Zaffora Blando
doaj  

The Undertesting Bias in Clinical Decision Making: The Role of Test Dichotomization. [PDF]

Med Decis Making
Mungan MC.
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Patients' Perspectives on Applications of AI and Personalized Medicine in Life-Threatening Heart Disease: European Cross-Sectional Patient Questionnaire Study. [PDF]

J Med Internet Res
Lindinger GL, Schiermeier NJ, Willems DL, Maris MT, Khattab M, Tan HL, Henzler D, Bak MAR, Nagel E, Lauerer M.   +9 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Models of Deferred Decision Making.

, 2014
Hotaling, Jared, Rieskamp, Jorg, Gluth, Sebastian   +2 more
openaire   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Personalized Medicine in Pediatric Urology: From Diagnosis to Individualized Risk Assessment. [PDF]

Med Sci (Basel)
Pogorelić Z, Cvitković Roić A.
europepmc   +1 more source