Results 221 to 230 of about 3,307,600 (301)

Leveraging chatbots for enhanced decision-making: a comprehensive literature review. [PDF]

Front Artif Intell
Simelane PM, Kittur J.
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Editorial: Neurocomputational models of decision-making and cognitive processes

Frontiers in Human Neuroscience
Lidia Ghosh, Anuradha Saha
doaj   +1 more source

Fuzzy decision support systems for hospital infection management: a circular q-ROF CRADIS method to prevention and control. [PDF]

Sci Rep
Li M, Wang R, Wang M, Zhao Y, Shen X.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Research priorities for improved pandemic and epidemic intelligence.

Lancet Glob Health
Tornimbene B, Redies I, AbdelMalik P, Abernethy J, Anton N, Awofisayo-Okuyelu AA, Fitzner J, Franz C, Ghozzi S, Golding J, Haouala A, Hersey S, Imai-Eaton N, Kampmann B, Krause G, Lais RS, de Waroux OLP, Carrera RM, Ngamala PN, Norton A, Ross AL, Sangameshwaran R, Van der Zee M, Wymer E, Morgan O.   +24 more
europepmc   +1 more source

Experiences, perceptions and preferences regarding medical decision-making in South Korea: a nationwide cross-sectional survey of the general public. [PDF]

BMJ Open
Kim MJ, Yoo SH.
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Contributions of Artificial Intelligence to Decision Making in Nursing: A Scoping Review. [PDF]

Nurs Health Sci
Fernandes F, Shinners L, Mota M, Santos P, Sá L.   +4 more
europepmc   +1 more source