Results 81 to 90 of about 40,912 (253)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The Role of Father and Mother Attachment on The Career Decision-Making Style of Female Balinese High School Students

Jurnal Psikiatri Surabaya
Introductions: Career decision-making in female Balinese high school students is influenced by parental attachment, particularly in a patriarchal cultural context.
Laksmi Ananda Dewi, Luh Kadek Pande Ary Susilawati   +1 more
doaj   +1 more source

Gaya Pengambilan Keputusan Kepala Sekolah dalam Meningkatkan Efektivitas Sekolah pada SMA Negeri di Kecamatan Kairatu Kabupaten Seram Bagian Barat

Edukasia, 2023
Decision making plays an important role in improving School Effectiveness. Principals can use various styles such as authoritative, consultative, delegative, facilitative and flexible styles, Rahabav (2021). Style variations in principal decision making
Welly Tomatala, Izaak Hendrik Wenno, Th. Laurens   +2 more
doaj  

Nurses’ decision-making style in hospital settings

Revista Brasileira de Enfermagem
ABSTRACT Objectives: to analyze nurses’ decision-making styles in hospital settings and to associate their sociodemographic and occupational profiles with their decision-making styles. Methods: this is a quantitative, analytical study conducted with 181 nurses from a public university hospital in southern Brazil.
Patrícia Soares Freitas Caetano, Thaís Victor Marques, Vivian Vitória Maciel, Walison Alves Movio, Aroldo Gavioli, Maria do Carmo Fernandez Lourenço Haddad, Patrícia Aroni Dadalt   +6 more
openaire   +3 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source