Results 101 to 110 of about 709,268 (298)

GAYA BERPIKIR, GAYA PEMECAHAN MASALAH, DAN GAYA PENGAMBILAN KEPUTUSAN PADA USIA PRODUKTIF [PDF]

, 2016
Penelitian ini dilakukan untuk melihat pengaruh antara gaya berpikir, gaya pemecahan masalah, dan gaya pengambilan keputusan pada individu usia produktif. Pendekatan kuantitatif dengan metode korelasi digunakan dalam penelitian ini.
Maniatinupus, Luluatnul Jannah
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

New service development in high tech sectors: a decision making perspective [PDF]

Many service companies active in high tech sectors have implemented largely decentralized decision architectures in their innovation processes. This is done to improve responsiveness under extremely dynamic and uncertain business conditions.
Lievens,Annouk, Riel,Allard C.R.,van
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Leadership Styles and Decision-making in Finnish and Swedish Organizations [PDF]

Globalization and other forces are challenging the European leadership models and practices. It can be seen that albeit what’s a very efficient leadership style for one country may be an extremely ineffective style for another - people aren’t always ...
Tuija LAMSA
core  

Cyber peers’ influence for adolescent consumer in decision-making styles and online purchasing behavior [PDF]

[[abstract]]Nowadays, there is a boom in online purchasing, especially by adolescents. In fact, scholars and marketers alike have long noticed the emergence of adolescent consumers and their consumption behaviors.
Ariely, Arnett, Arnett, Bearden, Bearden, Beaudoin, Belk, Berndt, Burnkrant, Cohen, Coleman, Darden, Durkin, Durvasula, Engel, Engel, Engles, Ferle, Fullerton, Furnham, Hafstrom, Jonathan, Kamaruddin, Kelman, Kotler, Kraut, Kwan, Lin, Mack, McAlister, McDonald, Menasce, Moschis, Moschis, Newman, Niu, Noble, Park, Pincus, Santrock, Schiamberg, Schiffman, Shepherd, Shim, Shim, Sproles, Sproles, Stone, Tai, Tauber, Wesley, Yang   +51 more
core   +1 more source

Strategic Decision Making Practice In Croatia – Which Decision Making Style Is More Effective?

World academy of science, engineering and technology, 2014
{"references": ["S. Elbanna and J. Child, \"Influences on strategic decision effectiveness:\nDevelopment and test of an integrative model\" Strategic Management\nJournal, vol. 28, 2007, pp. 431-453.", "H. Mintzberg, D. Raisinghani and A. Theoret, \"The Structure of\nUnstructured Decision Processes\", Administrative Science Quarterly,\nvol. 21, no.
openaire   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source