Results 91 to 100 of about 2,185,301 (307)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Design a decision-making aid: "alternative treatment for breast cancer: what option do you prefer?"

open access: yesPsicooncologia, 2010
Purpose: To design a Decision-making Aid within the ‘Breast cancer’ healthcare process modelling of the Andalusian Public Health System (SSPA) for the therapeutic approach of early-stage disease.
Carmen Pérez   +12 more
doaj  

On the Channel and Type of Aid: The Case of International Disaster Assistance [PDF]

open access: yes
The aim of this paper is to determine the drivers of a donor’s decision on the composition of aid. We apply a dataset on international post-disaster assistance between 2000 and 2007 that includes information on the channel (bilateral vs.
Manijeh Schwindt, Paul A. Raschky
core  

The evaluation of a breast cancer screening decision aid in the community setting. [PDF]

open access: yes, 2018
Breast cancer screening (BCS) has been recommended to women by healthcare providers as well as professional organizations and non-profit awareness organizations for over four decades.
Gibbons, Kimberly
core   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Empirical evidence on the new international aid architecture [PDF]

open access: yes
We conduct an empirical study on how 22 donors allocate their bilateral aid among 147 recipient countries over the 1970-2004 period to investigate whether recent changes in the international aid architecture at the international and country levelhave led
Danny Cassimon, Stijn Claessens
core   +3 more sources

Development of a Patient Decision Aid on the Choice of Diabetes Medication for Filipino Patients with Type 2 Diabetes Mellitus

open access: yesJournal of the ASEAN Federation of Endocrine Societies, 2019
Objective. To develop a locally adapted patient decision aid (PtDA) on treatment intensification among Filipino patients with Type 2 Diabetes Mellitus and to test the feasibility of using PtDAs in a low middle-income country. Methodology. A qualitative
Anna Angelica Macalalad-Josue   +3 more
doaj   +1 more source

Diverter AI based decision aid, phases 1 and 2 [PDF]

open access: yes
It was determined that a system to incorporate artificial intelligence (AI) into airborne flight management computers is feasible. The AI functions that would be most useful to the pilot are to perform situational assessment, evaluate outside influences ...
Bayles, Scott J.   +4 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Patient Education on the Association of Hormonal Contraception with Depression [PDF]

open access: yes, 2019
Hormonal contraceptive agents are widely used by women during their reproductive years. In recent years, research has been released linking hormonal contraception with the initiation of antidepressant medication and a first diagnosis of depression.
Hannigan, Julia E
core   +1 more source

Home - About - Disclaimer - Privacy