Results 81 to 90 of about 4,224,526 (303)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Christian Aid and Pro-poor Market Development [PDF]
, 2012 Christian Aid Briefing PaperChristian Aid believes that by pursuing more market-orientated approaches we can create opportunities for enterprises run by poor people to grown in scale, profitability and strength, so that they are less likely to fail when ...
Clare Clifton, James Cannon
core
Structuring as an Aid to Performance in Base-Rate Problems [PDF]
, 1984 41 pagesFour groups of college students were each given two base-rate problems. Three of the groups were given an aid with the first problem: (a) An instruction to list factors or aspects that were relevant to solving the problem, (b) a fill-in-the ...
Lichtenstein, Sarah +1 more
core +1 more source
Shared Decision-Making and Patient Decision Aids [PDF]
Circulation: Cardiovascular Quality and Outcomes, 2012 The quality and cost of medical care is determined in large part by the decisions that clinicians and patients make every day about seeking care, having tests, starting treatments, and stopping treatments. There are situations in medicine in which a treatment or approach has considerable evidence of significant benefit with minimal or no harm.
openaire +2 more sources
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
A decade of application of the Choquet and Sugeno integrals in multi-criteria decision aid [PDF]
The main advances regarding the use of the Choquet and Sugeno integrals in multi-criteria decision aid over the last decade are reviewed. They concern mainly a bipolar extension of both the Choquet integral and the Sugeno integral, interesting particular
Michel Grabisch, Christophe Labreuche
core
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
323 - Smart Electronic BPH Decision Aid Tool
ContinenceHypothesis / aims of study: Benign prostate hyperplasia (BPH) is highly prevalent and ever rising in an ageing population, becoming the leading cause of lower urinary tract symptoms in men.
M El Bahnasawi, D Swan, A Becky
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source