Results 81 to 90 of about 354,100 (264)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

The Future of Health Is Self-Production and Co-Creation Based on Apomediative Decision Support

Medical Sciences, 2018
Cultural changes are needed in medicine if the benefits of technological advances are to benefit healthcare users. The Digital Health Manifesto of ‘medical futurist’ doctor Bertalan Meskó and ‘e-patient’ Dave deBronkart ...
Jack Dowie, Mette Kjer Kaltoft
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Design a decision-making aid: "alternative treatment for breast cancer: what option do you prefer?"

Psicooncologia, 2010
Purpose: To design a Decision-making Aid within the ‘Breast cancer’ healthcare process modelling of the Andalusian Public Health System (SSPA) for the therapeutic approach of early-stage disease.
Carmen Pérez, Carmen Domínguez, Enrique Alonso, M. Mercedes Acebal, Guadalupe Carmona, Marina Álvarez, Basilio Dueñas, Araceli Caro, M. Ángeles Hernández, José Luis Padilla, Juan Antonio Virizuela, Eloisa Bayo, José Andrés Moreno   +12 more
doaj  

Maintaining Accuracy While Reducing Effort in Online Decision Making: A New Quantitative Approach for Multi-Attribute Decision Problems Based on Principal Component Analysis

Journal of Theoretical and Applied Electronic Commerce Research
This paper explores consumer decision making, particularly focusing on the increasing prevalence of choices on the Internet such as online shopping. Examining the fundamental question of how individuals decide how to decide, our paper draws upon the ...
Herbert Jodlbauer, René Riedl
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

‘This workshop was bright and beautiful’: insights into the process of co-production of images for decision aids with marginalised groups

Research for All
This co-production project worked with groups often marginalised in research, in order to improve the accessibility and inclusivity of two online patient decision aids through the use of images.
doaj   +2 more sources

Design a decision-making aid: "alternative treatment for prostate cancer: what option do you prefer?"

Psicooncologia, 2010
Purpose: To design a Decision-making Aid within the ‘Benign Prostatic Hyperplasia’ healthcare process modelling of the Andalusian Public Health System (SSPA) for the therapeutic approach of early-stage disease.
Carmen Pérez, Enrique Alonso, Guadalupe Carmona, Araceli Caro, José Luis Padilla, Víctor Baena, Francisco J. Torrubia, María Josefa Requena, Ismael Herruzo, Ramón Linares, Reyes Sanz, José Luis Soler, Pedro Pablo Pérez, Juan Carlos Villalobos   +13 more
doaj  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Time required to implement a computerized patient decision aid for lupus in outpatient visits

Implementation Science Communications
Background Patient decision aids have the potential to lower decision conflict for patients and to improve patient-physician communication. However, uptake of decision aids has been poor, in part because the time required to incorporate these into ...
Nathan W. Carroll, Aizhan Karabukayeva, Larry R. Hearld, Diane Kamen, Alfred H. J. Kim, Sonali Narain, Narender Annapureddy, Zineb Aouhab, Maureen McMahon, Vikas Majithia, Cathy Lee Ching, Winn Chatham, Jasvinder A. Singh   +12 more
doaj   +1 more source