Results 121 to 130 of about 2,185,301 (307)
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Health ExpectationsBackground Decisions about driving for individuals living with dementia (ILWD) can be challenging. There are limited evidence‐based person‐centred interventions in the United Kingdom that support decisions about transitioning to not driving or guidelines
Nadine Veerhuis +5 more
doaj +1 more source
Integrated assessment of biological invasions [PDF]
An assessment of the consequences of biological invasions and of the measures taken against must be at the base of each social decision in this field.
Rauschmayer, Felix
core
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Donor fragmentation and bureaucratic quality in aid recipients [PDF]
This paper analyzes the impact of donor fragmentation on the quality of government bureaucracy in aid-recipient nations. A formal model of a donor's decision to hire government administrators to manage donor-funded projects predicts that the number of ...
Knack, Stephen, Rahman, Aminur
core
Financial Planning for a Farmer Undergoing Organic Conversion [PDF]
, 2009 The switch to organic farming may be the biggest farm management decision you ever undertake so careful planning is essential. The vast majority of organic farmers have no regrets once converted.
Clavin, Dan
core
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
The design decision trail [PDF]
, 2012 This was a published paper presented at the International Conference on Engineering and Product Design Education on the 6th and 7th of September 2012 at the Artisis University College, Antwerp, Belgium.
Attenburrow, Derek H
core
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source