Results 91 to 100 of about 906,473 (303)

Shared decision-making and patient decision aids in dermatology [PDF]

, 2016
Shared decision making combines individual patient interests and values with clinical best evidence under the guiding principle of patient autonomy. Patient decision aids can support shared decision making and facilitate decisions that have multiple ...
Albrecht, Elwyn, Graham, Haynes, Kiesler, Stacey, Stacey, Tan, Tan, Tan, Towle, Walter   +11 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Research progress of shared decision⁃making in labor analgesia

Huli yanjiu, 2022
This paper reviewed the concept，connotation，decision⁃making aids， decision⁃making steps， and clinical application of shared decision⁃making in labor analgesia，analyzed the challenges，and put forward the development strategies.
GAO Han, TIAN Xuejun, YANG Zheng, CHEN Xiao   +3 more
doaj  

Cómo mejorar la comprensión y comunicación de información sobre riesgos médicos y salud [PDF]

, 2014
Informed and shared decision making require that people understand health risks. Unfortunately, many people are not risk literate and are biased by common risk communication practices.
García-Retamero Imedio, Rocío
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Preference-sensitive decisions of patients with metastatic breast cancer: The need for decision support

Patient Experience Journal, 2016
Because of disease progression and the increasing number of treatment options, patients with metastatic breast cancer face multiple decisions over time.
Julie van de Haterd, Helene Voogdt-Pruis, Ilse Raats, Rianne van den Brink, Haske van Veenendaal   +4 more
doaj  

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Experience in a Climate Microworld: Influence of Surface and Structure Learning, Problem Difficulty, and Decision Aids in Reducing Stock-Flow Misconceptions

Frontiers in Psychology, 2018
Research shows that people’s wait-and-see preferences for actions against climate change are a result of several factors, including cognitive misconceptions.
Medha Kumar, Varun Dutt, Varun Dutt
doaj   +1 more source