Results 101 to 110 of about 193,992 (310)

Patient decision aids in routine maternity care: Benefits, barriers, and new opportunities

, 2015
Background and aim: Participation in decision-making, supported by comprehensive and quality information provision, is increasingly emphasised as a priority for women in maternity care.
Thompson, Rachel, Miller, Yvette D., Watson, Bernadette, Stevens, Gabrielle   +3 more
core   +1 more source

Preference-sensitive decisions of patients with metastatic breast cancer: The need for decision support

Patient Experience Journal, 2016
Because of disease progression and the increasing number of treatment options, patients with metastatic breast cancer face multiple decisions over time.
Julie van de Haterd, Helene Voogdt-Pruis, Ilse Raats, Rianne van den Brink, Haske van Veenendaal   +4 more
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Guidelines for using HIV testing technologies in surveillance: selection, evaluation, and implementation [PDF]

[UNAIDS/WHO Working Group on Global HIV/AIDS and STI Surveillance]."WHO/CDS/CSR/EDC/2001.16.""UNAIDS/01.22E.""Global surveillance of HIV/AIDS and sexually transmitted infections (STIs) is a joint effort of the World Health Organization (WHO) and the ...
UNAIDS/WHO Working Group on Global HIV/AIDS and STI Surveillance
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Experience in a Climate Microworld: Influence of Surface and Structure Learning, Problem Difficulty, and Decision Aids in Reducing Stock-Flow Misconceptions

Frontiers in Psychology, 2018
Research shows that people’s wait-and-see preferences for actions against climate change are a result of several factors, including cognitive misconceptions.
Medha Kumar, Varun Dutt, Varun Dutt
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Clinical decision aids for chest pain in the emergency department: identifying low-risk patients

, 2015
William Alley, Simon A Mahler Department of Emergency Medicine, Wake Forest Baptist Medical Center, Winston-Salem, NC, USA Abstract: Chest pain is one of the most common presenting complaints in the emergency department, though only a small minority of ...
Mahler SA, Alley W
core  

National AIDS Control Programme Ministry of Health

, 2021
This report is published by the Department of Aids Control on a monthly basis. The major objectives of the publication are to Notify the current status of AIDS epidemic in the country, and provide information for decision making and future ...
National AIDS Control Programme Ministry of Health
core