Results 131 to 140 of about 193,992 (310)

Evaluation of a Decision Aid for the Classification of Microcalcifictions

, 1998
The aim of this work is to provide radiologists with a computerised decision aid. We use the term ‘decision aid’ to indicate a system which makes available small amounts of relevant information on the basis of patient data. In a previous paper we reviewed a variety of approaches being used in systems to assist radiological decision making, approaches ...
Taylor, P, Fox, J, Todd-Pokropek, A
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Perceptual change through transnational experience : American exchange students and HIV/AIDS

, 2008
Includes bibliographical references (p. 83-97).Includes abstract.This thesis considers the power of United States popular media to construct both conceptions of "Africa" and knowledge of HN / AIDS among exchange students in Cape Town, South Africa ...
Abrams, Amber
core  

Implementing decision aids for cardiovascular disease prevention: stakeholder interviews and case studies in Australian primary care [PDF]

BACKGROUND: Australian cardiovascular disease (CVD) prevention guidelines recommend absolute CVD risk assessment, but less than half of eligible patients have the required risk factors recorded due to fragmented implementation over the last decade.
Doust, Jenny, de Wet, Carl, Greaves, Kim, Batcup, Carys, Crosland, Paul, Chapman, Niamh, Hawkes, AL, Bonner, Carissa, Cornell, Samuel, Chapman, N, Greaves, K, Morgan, Mark, Hawkes, Anna L, O'Connor, Denise, O’Connor, D, Pickles, Kristen, Cornell, S, Bonner, C, Batcup, C, de Wet, C, Crosland, P, Pickles, K, Morgan, M, Doust, J   +23 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Development and application of culturally appropriate decision aids for smoking cessation in Korea: a pragmatic clustered randomization crossover trial

, 2016
Ji Eun Lee,1 Dong Wook Shin,1–3 Beomseok Suh,1 Sohyun Chun,4 You-Seon Nam,3 Belong Cho1,2 1Department of Family Medicine, Health Promotion Center, 2Laboratory of Health Promotion and Health Behavior, Biomedical Research Institute, Seoul National ...
Suh B, Lee JE, Nam YS, Chun S, Cho B, Shin DW   +5 more
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Knowledge of HIV and AIDS in women in sub-Saharan Africa

, 2008
Although most African people have heard of HIV and AIDS, there is still widespread misunderstanding about how HIV is spread, the consequences of infection, and how to protect against infection.
Drummond, P.D., Burgoyne, A.D., Burgoyne, AD, Drummond, PD   +3 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source