Results 81 to 90 of about 26,255,985 (305)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
Boundary Value Problems, 2018 In this work, a biharmonic elliptic system is investigated in RN $\mathbb{R}^{N}$, which involves singular potentials and multiple critical exponents. By the Rellich inequality and the symmetric criticality principle, the existence and multiplicity of G ...
Zhiying Deng, Dong Xu, Yisheng Huang
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Evolution of hotspots and research trends in agricultural mulch film research: a bibliometric review
Frontiers in Environmental ScienceAgricultural mulch film (AMF) can increase the soil temperature, reduce the evaporation of water and soil erosion, control the number of weeds and pests, and improve the yield and quality of crops.
Kuaishun Wang +6 more
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Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito +7 more
wiley +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Fixed-Time Connectivity Preserving Tracking Consensus of Multiagent Systems with Disturbances
Complexity, 2020 This text studies the fixed-time tracking consensus for nonlinear multiagent systems with disturbances. To make the fixed-time tracking consensus, the distributed control protocol based on the integral sliding mode control is proposed; meanwhile, the ...
Fenglan Sun +3 more
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Clinical Decision Analysis using Decision Tree [PDF]
Epidemiology and Health, 2014 The clinical decision analysis (CDA) has used to overcome complexity and uncertainty in medical problems. The CDA is a tool allowing decision-makers to apply evidence-based medicine to make objective clinical decisions when faced with complex situations. The usefulness and limitation including six steps in conducting CDA were reviewed.
openaire +3 more sources