Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
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Leadless Pacing and the Emerging Era of Combined Procedures in Adult Congenital Heart Disease. [PDF]
Das S, Karolcik BA, Howard TS.
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The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
From prediction to action-Making emergency laparotomy risk scores clinically usable. [PDF]
Vijayaraghavalu S.
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Quantum Computing and Quantum Technologies in Drug Discovery and Therapeutics: Evidence, Benchmarking, and Translational Integration. [PDF]
Niazi SK.
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Current Clinical Utility of Gene Expression Panels in Primary Cutaneous Melanoma. [PDF]
Garza TL +8 more
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Pharmacogenomic Stratification for Oncology Drug Repurposing: An Exposure Target Context Eligibility Framework. [PDF]
El-Tanani M +5 more
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Re-thinking funding success in Alzheimer's disease research: Why good science is not enough. [PDF]
Fusdahl P, Borda MG, Aarsland D.
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Pharmacotherapy Risks in Rare Genetic Diseases: Cross-Referencing ACMG Secondary Findings v3.2 List With Clinical Databases. [PDF]
Allen JD, Duong BQ, Vogt J, Arn P.
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