Results 91 to 100 of about 2,930,808 (249)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Peranan Decision Support System (DSS) bagi Manajemen Selaku Decision Maker [PDF]

open access: yes, 2012
The rapidly technology process on globalisasion era in business world, makes the decision making is the important thing to make decision faced with the competition in business world.
Whetyningtyas, Aprilia
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Sesión de Clausura Primeras Jornadas MAKER STREAHM

open access: yes, 2019
17:30 Ceremonia de clausura Dra. Claudia Marina Vicario Solórzano Dr. Salvador Isidro Belmonte Jiménez Ing.
Miembros de la, Comunidad RedLaTE
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

A trapezoidal intuitionistic fuzzy optimization approach for crashing a budget constrained project

open access: yesAin Shams Engineering Journal
While the classical fuzzy applications have gained popularity in many different areas, intuitionistic fuzzy set theory emerged as an advancement to better identify various complex circumstances such as the hesitancy of a decision maker under uncertainty.
Fatih Kasimoglu   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

When a Surrogate Knows What to Do, but Can’t Do It

open access: yesCanadian Journal of Bioethics
A surrogate or substitute decision-maker is tasked with making medical choices that the patient would make for themselves. However, most of the time the surrogate decision-maker is also emotionally involved with the patient, which makes the execution of
Victor Esteban Grado   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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