Results 101 to 110 of about 2,930,808 (249)

Boiler maker.

Editors: Dec. 1904-Mar. 1906, A. H. Sherwood; July 1907-1933, H. H. Brown.Imprint varies: - , New York : Boiler Maker; -Apr. 1920, New York ; London : Aldrich Publishing Co.; May 1920-1933, Philadelphia : Simmons-Boardman Publishing Corporation ...
Brown, Howard Hayes, 1884-, Sherwood, Arthur H.   +1 more
core  

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Land Grant Application- Maker, Burton (Harwich) [PDF]

, 2017
Land grant application submitted to the Maine Land Office for Burton Maker for service in the Revolutionary War.https://digitalmaine.com/revolutionary_war_mass/1224/thumbnail ...
Maker, Burton
core  

The vascular endothelium as decision maker in lung injury

Frontiers in Cell and Developmental Biology
The vascular endothelium is the largest organ in the human body, capable of performing a wide range of cellular signaling and synthetic functions. It is also subjected to considerable mechanical stress due to the shear forces generated by blood flow ...
Diana Klein
doaj   +1 more source

Interactive Multiobjective Fuzzy Random Linear Programming through Fractile Criteria

Advances in Fuzzy Systems, 2012
We propose an interactive fuzzy decision making method for multiobjective fuzzy random linear programming problems through fractile criteria optimization.
Hitoshi Yano, Masatoshi Sakawa
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

ROLE OF MENTAL MODELS IN COMMAND AND CONTROL

Sučasnì Informacìjnì Tehnologìï u Sferì Bezpeki ta Oboroni, 2014
The article describes and analyzes the main approaches to command and control. Their positive and negative sides were determined. The most effective command and control approach is offered based on the analysis.
Victor E. Bobylov, Serhii M. Kononenko
doaj