Results 91 to 100 of about 9,040,288 (288)
SEPHYRES: A Medical Diagnosis Model based on Semantic Pseudo-Fuzzy Plan and Radar-form Interface
Applied Medical Informatics, 2017 Clinical decision support systems have emerged to help users and patients. Despite the exciting developments, physicians still have not fully accepted and included the decision support systems in daily practice.
Ali SANAEIFAR +4 more
doaj
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Imperfections of XAI: Phenomena Influencing AI-Assisted Decision-Making [PDF]
With the increasing use of AI, recent research in human–computer interaction explores Explainable AI (XAI) to make AI advice more interpretable. While research addresses the effects of incorrect AI advice on AI-assisted decision-making, the impact of ...
Perer, Adam +5 more
core +1 more source
Evaluation of Building Design Variants in Early Phases on the Basis of Adaptive Detailing Strategies
BuildingsDesign decisions made in the early phases of the design process have a significant impact on the eventual performance of the completed building. Currently, computer-assisted methods offer limited support during the crucial stages of creating, assessing ...
Daniel Napps +12 more
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
Parity Assisted Decision Making for QAM Modulation [PDF]
, 2006 This paper discusses parity assisted decision making for QAM ...
Akl, Robert G. +2 more
core
Artificial Authority: The Promise and Perils of LLM Judges in Healthcare
BioengineeringBackground: Large language models (LLMs) are increasingly integrated into clinical documentation, decision support, and patient-facing applications across healthcare, including plastic and reconstructive surgery.
Ariana Genovese +7 more
doaj +1 more source