Results 121 to 130 of about 2,826,372 (331)
Organizational design of multi-product multi-market firms [PDF]
In this paper, we seek to understand how a multi-product multi-market firm (for example, a multinational firm) designs its organizational structure and compensation scheme when its profitability is conditioned by how market information flows within the ...
Joaquín Coleff
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Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
COMMUNICATIONS IN THE ORGANIZATIONAL D
IJLRES (International Journal on Language Research and Education Studies), 2017 This study aims to explore the extent to which communication can resolve conflicts within the organization. Conflict within the organization can occur at any time, either in the form of conflict between individuals as members of the organization, as ...
Fifi Hasmawati
doaj
Applied SciencesArtificial intelligence, particularly machine learning, has revolutionized organizational decision-making processes by assuming many decision responsibilities traditionally allocated to humans.
Silvia Marocco +2 more
doaj +1 more source
How should a principal delegate a task to an agent? This paper studies the choice of an agent's discretion as a contracting problem. We show that the agent's freedom of action can be used as an effective incentive device: the agent's initiative is ...
Dezso Szalay
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Public Education Network 2004 Annual Member Survey [PDF]
, 2004 Each year for the past nine years, PEN has undertaken a survey of its members to chart organizational and programmatic characteristics of LEFs. In addition to providing valuable information about individual LEFs, each year's survey results provide a ...
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Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Group Maintenance Behaviors in the Decision-Making Styles of Self-Organizing Distributed Teams [PDF]
, 2009 Businesses, universities, and other organizations are increasingly reliant on self-organizing, distributed teams which are enabled by information and communication technologies (ICTs).
Crowston, Kevin +3 more
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Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source