Results 121 to 130 of about 12,156,070 (400)

Dynamic Non-Bayesian Decision Making

open access: yes, 1997
The model of a non-Bayesian agent who faces a repeated game with incomplete information against Nature is an appropriate tool for modeling general agent-environment interactions.
Monderer, D., Tennenholtz, M.
core   +3 more sources

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

The Ladder Theory of Behavioral Decision Making [PDF]

open access: yesarXiv, 2018
We study individual decision-making behavioral on generic view. Using a formal mathematical model, we investigate the action mechanism of decision behavioral under subjective perception changing of task attributes. Our model is built on work in two kinds classical behavioral decision making theory: "prospect theory (PT)" and "image theory (IT)".
arxiv  

Brucella NyxA and NyxB dimerization enhances effector function during infection

open access: yesFEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre   +4 more
wiley   +1 more source

Artificial Intelligence and Surgical Decision-Making.

open access: yesJAMA Surgery, 2019
Importance Surgeons make complex, high-stakes decisions under time constraints and uncertainty, with significant effect on patient outcomes. This review describes the weaknesses of traditional clinical decision-support systems and proposes that ...
T. Loftus   +8 more
semanticscholar   +1 more source

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

Fault-tolerant communication topology management based on minimum cost arborescence for leader–follower UAV formation under communication faults

open access: yesInternational Journal of Advanced Robotic Systems, 2017
A novel fault-tolerant communication topology management method for the leader–follower unmanned aerial vehicle (UAV) formation is proposed to minimize the formation communication cost while keeping the formation shape, even in the case of communication ...
Guoqiang Wang   +4 more
doaj   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Mandatory age verification for pornography access: Why it can't and won't ‘save the children’

open access: yesBig Data & Society
Age verification is currently gaining traction among some western democracies as a means to restrict minors’ access to online pornography. In this article we consider the ramifications of applying age estimation software to this task. We analyse a public
Zahra Stardust   +3 more
doaj   +1 more source

Decision making via generalized Bajraktarević means [PDF]

open access: yesarXiv, 2020
We define decision-making functions which arise from studying the multidimensional generalization of the weighted Bajraktarevi\'c means. It allows a nonlinear approach to optimization problems. These functions admit several interesting (from the point of view of decision-making) properties, for example, delegativity (which states that each subgroup ...
arxiv  

Home - About - Disclaimer - Privacy