Results 121 to 130 of about 7,021,374 (331)
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Large pragmatic randomised controlled trials in peri‐operative decision making: are they really the gold standard? [PDF]
, 2018 Girish P. Joshi +2 more
openalex +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Scientific ReportsMotor resonance (MoR) refers to the automatic activation of motor circuits during action observation, reflecting an internal simulation of the observed movement.
Carlos Nieto-Doval +6 more
doaj +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
International Journal for Equity in HealthObjectives To explore the perceptions that Colombians have about voluntary private health insurance plans (VPHI) in the health system to identify the tensions that exist between the public and private systems.
Daniel Felipe Patiño-Lugo +8 more
doaj +1 more source
Translation and cultural adaption of Observer OPTION5 and OPTION12 in a Danish context
Health Literacy and Communication OpenBackground and aim The aim of this study was to translate and culturally adapt the Observer scales OPTION5 and OPTION12 into Danish to improve the accessibility of the scales for all healthcare professionals and patients as co-researchers to objectively ...
Bettina Mølri Knudsen +2 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Humanities & Social Sciences CommunicationsDuring China’s critical period of industrial structural transformation, the relationship between digital finance, industrial structure upgrading, and energy efficiency has become a crucial issue that urgently requires exploration in the process of ...
Haicheng Zhu +4 more
doaj +1 more source