Results 131 to 140 of about 11,731,529 (403)

Mandatory age verification for pornography access: Why it can't and won't ‘save the children’

open access: yesBig Data & Society
Age verification is currently gaining traction among some western democracies as a means to restrict minors’ access to online pornography. In this article we consider the ramifications of applying age estimation software to this task. We analyse a public
Zahra Stardust   +3 more
doaj   +1 more source

The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity

open access: yesFEBS Letters, EarlyView.
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

THE EVIDENCE FOR A DECISION-MAKING THEORY OF VISUAL DETECTION [PDF]

open access: green, 1955
John A. Swets   +3 more
openalex   +1 more source

Making a Decision on Ethical Decision-Making Models

open access: yes, 2020
Those in the helping professions, like psychology, counseling, and social work, have numerous ethical guidelines and codes to dictate ethical behavior. These codes, while extensive, do not encompass all situations. When professionals find themselves in an ambiguous situation, it is called an ethical dilemma.
openaire   +3 more sources

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Effectiveness of an object moving depending on its orientation in the environment: a kinematic analysis of motor planning and execution

open access: yesНервно-мышечные болезни
Background. Grasping objects with the hand is one of the most common movements in everyday life. It requires training involving the cognitive processes of goal selection and motor planning.Aim.
A. O. Vyazmin   +5 more
doaj   +1 more source

Transcranial magnetic stimulation with electroencephalography: methodology, applications for research and cilinics

open access: yesНервно-мышечные болезни, 2018
Combined use of transcranial magnetic stimulation and electroencephalography (TMS-EEG) is a highly informative cutting edge technology which is relevant for fundamental, clinical and  translational research. Unique capabilities of TMS-EEG approach  allow
M. A. Nazarova   +3 more
doaj   +1 more source

D numbers theory based game-theoretic framework in adversarial decision making under fuzzy environment [PDF]

open access: yesarXiv, 2017
Adversarial decision making is a particular type of decision making problem where the gain a decision maker obtains as a result of his decisions is affected by the actions taken by others. Representation of alternatives' evaluations and methods to find the optimal alternative are two important aspects in the adversarial decision making. The aim of this
arxiv  

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

open access: yesMolecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens   +8 more
wiley   +1 more source

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