Results 101 to 110 of about 12,247,022 (294)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Decision Making in Individualistic and Collectivistic Cultures [PDF]

open access: yes, 2004
How do cultural values influence individuals\u27 decision making? One would expect answers to this question either from cognitive psychology or from cross-cultural psychology.
C. Dominik Guess, Guess, C. Dominik
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Chapter 7 Aging, Memory, and Decision Making

open access: yes, 2015
Aging differentially affects diverse aspects of memory functioning. In turn, memory changes have specific effects on different judgment and decision-making tasks.
Nilsson, L-G   +2 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Can asymmetric subjective opportunity cost effect explain impatience in intertemporal choice? A replication study

open access: yes, 2019
In "The value of nothing: asymmetric attention to opportunity costs drives intertemporal decision making" Read, Olivola and Hardisty (2017) proposed an asymmetric subjective opportunity cost (ASOC) effect to explain and predict why impatience can be ...
Huang, Yuan-Na   +3 more
core   +3 more sources

Prediction models for COVID-19 clinical decision making

open access: yesThe Lancet: Digital Health, 2020
Artuur M Leeuwenberg, Ewoud Schuit
doaj   +1 more source

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