Results 121 to 130 of about 12,247,022 (294)
The interaction of fuzzy logic with machine learning and artificial intelligence in decision-making models [PDF]
The employment of fuzzy logic is progressively gaining recognition as a prevalent and extensive methodology across a diverse spectrum of decision-making procedures.
Nalbant, Kemal Gokhan
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Implications of integrating large language models into clinical decision making
Communications MedicineChristof & Armoundas explore how large language models (LLMs) can augment clinician-level clinical reasoning across the three pillars-framing the encounter, diagnostic reasoning, and treatment/management-highlighting gains in information synthesis and ...
Michael Christof, Antonis A. Armoundas
doaj +1 more source
Trustworthiness Evaluation of Large Language Models Using Multi-Criteria Decision Making
IEEE AccessAs Large language models (LLMs) become increasingly integrated into high-stakes applications, ensuring their trustworthiness has emerged as a critical research concern.
Meltem Aksoy +2 more
doaj +1 more source
Shared Decision-Making as a Model of Medical Decision-Making
Korean Journal of Medical Ethics, 2008 Matters related to human life and death and medical healing are the concerns of patients, physicians, and other related persons, including family members of the patients. Existing medical decision-making models include paternalism and informed consent. However, these models have the limitation of being one-sided or unidirectional. Accordingly, shared
openaire +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Leveraging Uncertainties in Softmax Decision-Making Models for Low-Power IoT Devices. [PDF]
Sensors (Basel), 2020 Cho C, Choi W, Kim T.
europepmc +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source