Results 171 to 180 of about 5,101,462 (320)

DISESOR - decision support system for mining industry [PDF]

Annals of computer science and information systems, 2015
Michał Kozielski, Marek Sikora, Łukasz Wróbel   +2 more
doaj   +1 more source

The Knowledge Connector decision support system for multiomics-based precision oncology. [PDF]

Nat Commun
Hübschmann D, Kreutzfeldt S, Roth B, Glocker K, Schoop J, Oeser L, Hausmann S, Koch C, Uhrig S, Hüllein J, Hutter B, Fröhlich M, Heilig CE, Teleanu MV, Lipka DB, Kerle IA, Baude-Müller A, Beck K, Heining C, Glimm H, Ückert F, Knurr A, Fröhling S, Horak P.   +23 more
europepmc   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Decision Support Systems used in Disaster Management

, 2010
Marius Cioca, Lucian-Ionel Cioc
openalex   +2 more sources

Critical impact of automobile industry with advanced decision support system and Aczél-Alsina Hammy mean operators. [PDF]

Sci Rep
Hussain A, Ullah K, Ali Z, Pamucar D.
europepmc   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Generation of intelligent reports for ubiquitous group decision support systems

, 2016
Luís Conceição, João Carneiro, Diogo Martinho, Goreti Marreiros, Paulo Nováis   +4 more
openalex   +2 more sources

Goal driven business modelling: supporting decision making within information systems development [PDF]

, 1995
Stephan Jacobs, Roland Holten
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Leveraging clinical decision support system tools for childhood overweight/obesity management. [PDF]

BMC Med Inform Decis Mak
Wardell JR, Shaska N, Ahmed Z, Gregg B, Singer K, Lee JE, Hirschfeld E, Garrity A, Woolford S, Peterson KE, Bragg-Gresham J, Orringer K, Oshman L, Gabison J, Mohammed L, Yoon E, Bilhartz J, Burns B, Lee JM.   +18 more
europepmc   +1 more source