Results 91 to 100 of about 3,873,412 (326)
THE COLLABORATIVE LEARNING SYSTEMS USED AS DECISION SUPPORT SYSTEMS [PDF]
This paper reviews a case study in the use of COST/BENEFIT ANALYSIS in project appraisal which serves to illustrate different aspects of the practical problem (using the CBA/PC package) and the Management Game “MANAGER” that simulate all functions for ...
Virgil Chichernea
core
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Designing Decision Support Systems for Emergency Response: Challenges and Opportunities [PDF]
, 2022 Geoffrey Pettet +6 more
openalex +1 more source
DECISION SUPPORT SYSTEMS FOR AGRICULTURE AND RURAL FUTURES [PDF]
Farm Management,
Fuller, Earl I.
core +1 more source
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
FEBS Letters, EarlyView.This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
Fuzzy logic–based clinical decision support system for the evaluation of renal function in post‐Transplant Patients [PDF]
, 2019 Giovanni Improta +4 more
openalex +1 more source
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
FEBS Letters, EarlyView.Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
Data Mining – Ein neues Paradigma der angewandten Statistik
Austrian Journal of Statistics, 2016 Im Rahmen dieses Beitrages wird versucht die Unterschiede im methodologischen Ansatz bei Verfahren des Data Mining den traditionellen statistischen Modellierungskonzepten gegenüberzustellen.
Marcus Hudec
doaj +1 more source