Results 91 to 100 of about 16,607,891 (208)

Multi-classifiers of Small Treewidth [PDF]

open access: yes, 2015
Multi-dimensional Bayesian network classifiers are becoming quite popular for multi-label classification. These models have the advantage of a high expressive power, but may induce a prohibitively high runtime of classification.
Pastink, A.J.   +8 more
core   +1 more source

Clinical decision support for immunization (CDSi) [PDF]

open access: yes
Immunization clinical decision support (CDS), more commonly referred to as evaluation and forecasting, is an automated process that determines the recommended immunizations needed for a patient and delivers those recommendations to the healthcare ...

core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

An architecture for organisational decision support [PDF]

open access: yes, 2007
The Decision Support (DS) topic of the Network Enabled Capability for Through Life Systems Engineering (NECTISE) project aims to provide organisational through-life decision support for the products and services that BAE Systems deliver.
Whitfield, R.I.   +4 more
core   +3 more sources

A Co-Creation Framework for Developing Digital Technology-Assisted Policy Adoption Roadmaps: Evidence from European Public Sector Case Studies

open access: yesApplied Sciences
Public administrations increasingly seek to adopt digital tools for evidence-based policymaking, yet systematic frameworks guiding this adoption remain scarce.
Panagiotis Kokkinakos   +6 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Credal Sum-Product Networks [PDF]

open access: yes, 2017
Sum-product networks are a relatively new and increasingly popular class of (precise) probabilistic graphical models that allow for marginal inference with polynomial effort. As with other probabilistic models, sum-product networks are often learned from
Decision Support Systems   +6 more
core   +1 more source

Explainable AI-Based Ensemble Clustering for Load Profiling and Demand Response

open access: yesEnergies
Smart meter data provide an in-depth perspective on household energy usage. This research leverages on such data to enhance demand response (DR) programs through a novel application of ensemble clustering.
Elissaios Sarmas   +2 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

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