Results 131 to 140 of about 7,106,023 (372)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Targeted Data Augmentation for Improving Model Robustness

International Journal of Applied Mathematics and Computer Science
This paper proposes a new and effective bias mitigation method called targeted data augmentation (TDA). Since removing biases is often tedious and challenging and may not always lead to effective bias mitigation, we propose an alternative approach ...
Mikołajczyk-Bareła Agnieszka, Ferlin Maria, Grochowski Michał   +2 more
doaj   +1 more source

A Fuzzy PROMETHEE Method for Evaluating Strategies towards a Cross-Country Renewable Energy Cooperation: The Cases of Egypt and Morocco

Energies
Recognising the urgency of addressing climate change and the imperative to mitigate its effects, the European Union (EU) has embarked on a transformative journey to reshape its energy landscape, with a pronounced emphasis on harnessing renewable energy ...
Aikaterini Papapostolou, Charikleia Karakosta, Filippos-Dimitrios Mexis, Ioanna Andreoulaki, John Psarras   +4 more
doaj   +1 more source

XWeB: the XML Warehouse Benchmark

, 2010
With the emergence of XML as a standard for representing business data, new decision support applications are being developed. These XML data warehouses aim at supporting On-Line Analytical Processing (OLAP) operations that manipulate irregular XML data.
A. Schmidt, A. Simitsis, C. Kit, J. Darmont, J. Gray, K. Runapongsa, L. Afanasiev, L. Wyatt, P. O’Neil, R. Kimball, R. Torlone, S. Bressan, S. Rizzi, T. Böhme   +13 more
core   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

The Need for Standards in Evaluating the Quality of Electronic Health Records and Dental Records: A Narrative Review

Big Data and Cognitive Computing
Over the past two decades, there has been an enormous growth in the utilization of electronic health records (EHRs). However, the adoption and use of EHRs vary widely across countries, healthcare systems, and individual facilities.
Varadraj P. Gurupur, Giang Vu, Veena Mayya, Christian King   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Innovative Business Models Towards Sustainable Energy Development: Assessing Benefits, Risks, and Optimal Approaches of Blockchain Exploitation in the Energy Transition

Energies
The goals of the European Union towards the energy transition imply profound changes in the energy field, so as to promote sustainable energy development while fostering economic growth.
Aikaterini Papapostolou, Ioanna Andreoulaki, Filippos Anagnostopoulos, Sokratis Divolis, Harris Niavis, Sokratis Vavilis, Vangelis Marinakis   +6 more
doaj   +1 more source

Modeling the Decision Support System in management of investment projects for prevention of emergency situations [PDF]

, 2017
Г. И. Горемыкина, O.V. Konstantinova, I.N. Mastyaeva   +2 more
openalex   +1 more source