Results 81 to 90 of about 13,550,266 (248)

Decision support for mastitis on farms with an automatic milking system [PDF]

open access: yes, 2010
For an optimal mastitis management on farms with an automatic milking system (AMS), two individual cow decisions are important. First, there is a need for decision support on which mastitis alerts have the highest priority for visual checking for ...
Dep Gezondheidszorg Landbouwhuisdieren   +3 more
core   +1 more source

Imagery, Affect, and Decision Making [PDF]

open access: yes, 1998
46 pagesTraditionally, the principal focus of research on judgment and decision making has been largely cognitive and rationalistic. More recently, however, decision-making researchers have acknowledged the role of non-cognitive factors and have ...
Paul Slovic   +5 more
core   +2 more sources

A decision support approach for sustainability management using multiple criteria decision making and statistical techniques

open access: yesSustainable Futures
In this paper, we derive a decision support tool to establish the policies a country may carry out to direct its performance toward the Sustainable Development Goals of the 2030 Agenda.
Ana B. Ruiz   +4 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

MEDICAL DECISION SUPPORT SYSTEM FOR HEPATITIS C VIRUS PREDICTION USING DATA MINING TECHNIQUES

open access: yesInternational Journal of Intelligent Computing and Information Sciences, 2014
The healthcare environment is generally perceived as being ‘information rich’ yet ‘knowledgepoor’. Which, unfortunately, are not “mined” to discover hidden information for effective decisionmaking by healthcare practitioners.
E Eliwa, T Mahmoud, M Girgis
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Are there any differences between features of proteins expressed in malignant and benign breast cancers?

open access: yesJournal of Research in Medical Sciences, 2010
Background: The most common cancer among women is breast cancer and it has been blamed as the second leading cause of cancer death in women; so far many approaches have been used to analyze and detect benign and malignant forms of cancer and ...
Mansour Ebrahimi   +3 more
doaj  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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