Results 81 to 90 of about 648,136 (315)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

MEDICAL DECISION SUPPORT SYSTEM FOR HEPATITIS C VIRUS PREDICTION USING DATA MINING TECHNIQUES

International Journal of Intelligent Computing and Information Sciences, 2014
The healthcare environment is generally perceived as being ‘information rich’ yet ‘knowledgepoor’. Which, unfortunately, are not “mined” to discover hidden information for effective decisionmaking by healthcare practitioners.
E Eliwa, T Mahmoud, M Girgis
doaj   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Decision-focussed resource modelling for design decision support

, 2009
Resource management including resource allocation, levelling, configuration and monitoring has been recognised as critical to design decision making. It has received increasing research interests in recent years. Different definitions, models and systems
Whitfield, R.I., Boyle, Iain, Duffy, A.H.B., Whitfield, Robert Ian, Liu, Shaofeng, Wang, Wenjuan, Mohamed, Khaled, Boyle, I.M., Liu, S., Duffy, Alex, Mohamed, K.   +10 more
core  

Are there any differences between features of proteins expressed in malignant and benign breast cancers?

Journal of Research in Medical Sciences, 2010
Background: The most common cancer among women is breast cancer and it has been blamed as the second leading cause of cancer death in women; so far many approaches have been used to analyze and detect benign and malignant forms of cancer and ...
Mansour Ebrahimi, Esmaeil Ebrahimie, Narges Shamabadi, Mahdi Ebrahimi   +3 more
doaj  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Explicit Modeling and Visualization of Imperfect Information in the Context of Decision Support for Tsunami Early Warning in Indonesia

, 2011
A certainty model and appropriate visualization techniques are presented which are applied in a newly developed Decision Support System (DSS) for tsunami early warning deployed in Jakarta, Indonesia.
Raape, Ulrich, Schoeckel, Thorsten, Friedemann, Monika, Sven Tessmann, Monika Friedemann, Thorsten Schoeckel, Strobl, Christian, Teßmann, Sven, Ulrich Raape, Christian Strobl   +9 more
core   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

FEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia, Anna Dósa, Asha Kiran Maddali, András Jipa, Hajnalka Laczkó‐Dobos, Péter Lőw, Gábor Juhász   +6 more
wiley   +1 more source

Decision support for build-to-order supply chain management through multiobjective optimization

, 2010
This paper aims to identify the gaps in decision-making support based on multiobjective optimization for build-to-order supply chain management (BTOSCM).
Gallear, D, Mansouri, A, Askariazad, M
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