Results 71 to 80 of about 398,474 (306)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Probabilistic Forecast for Real-Time Control of Rainwater Pollutant Loads in Urban Environments
HydrologyAdvanced wastewater management systems are necessary to effectively direct severely contaminated initial rainwater runoff to the treatment facility only when pollutant concentrations are elevated during the initial flush event, thereby reducing the risk ...
Annalaura Gabriele +3 more
doaj +1 more source
Navigating challenges in the insurance industry: A comparative MCDM analysis of developed and developing countries [PDF]
Yugoslav Journal of Operations ResearchInsurance Policy adoption is the key to a better and safer living whether it comes to the individual or a business setup. Over the years this sector has been exposed to various challenges, especially when it comes to stability and gaining the trust of ...
Gohar Ali
doaj +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Probabilistic/information gap decision theory‐based bilevel optimal management for multi‐carrier network by aggregating energy communities [PDF]
, 2023 Sobhan Dorahaki +4 more
openalex +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Uncertainty-Aware Multimodal Fusion and Bayesian Decision-Making for DSS
AppliedMathUncertainty-aware decision-making increasingly relies on multimodal sensing pipelines that must fuse correlated measurements, propagate uncertainty, and trigger reliable control actions. This study develops a unified mathematical framework for multimodal
Vesna Antoska Knights +3 more
doaj +1 more source
On the use of discrete-time quantum walks in decision theory. [PDF]
PLoS One, 2022 Chen M, Ferro GM, Sornette D.
europepmc +1 more source
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source