Results 81 to 90 of about 580,863 (315)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1535-1555, June 2026.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1591-1611, June 2026.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Uniform Sampling of the Infinite Noncooperative Game on Unit Hypercube and Reshaping Ultimately Multidimensional Matrices of Player’s Payoff Values

open access: yesElectrical, Control and Communication Engineering, 2015
The paper suggests a method of obtaining an approximate solution of the infinite noncooperative game on the unit hypercube. The method is based on sampling uniformly the players’ payoff functions with the constant step along each of the hypercube ...
Romanuke Vadim
doaj   +1 more source

Unraveling the dynamics of community-associated methicillin-resistant Staphylococcus aureus

open access: yes, 2013
Since the first description of the community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) strain USA300 [1] in the 1990s, this pathogen has emerged worldwide [2].
Bootsma, M.C.   +3 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

TWO MEASURES OF THE DEPENDENCE OF PREFERENTIAL RANKINGS ON CATEGORICAL VARIABLES

open access: yesStudies in Logic, Grammar and Rhetoric, 2017
The aim of this paper is to apply a general methodology for constructing statistical methods, which is based on decision theory, to give a statistical description of preferential rankings, with a focus on the rankings’ dependence on categorical variables.
Lissowski Grzegorz
doaj   +1 more source

Incentives for Crypto-Collateralized Digital Assets

open access: yesProceedings, 2019
Digital currencies such as Bitcoin frequently suffer from high price volatility, limiting their utility as a means of purchasing power. Hence, a popular topic among cryptocurrency researchers is a digital currency design which inherits the ...
Philip N. Brown
doaj   +1 more source

A species sampling model with finitely many types

open access: yes, 2010
A two-parameter family of exchangeable partitions with a simple updating rule is introduced. The partition is identified with a randomized version of a standard symmetric Dirichlet speciessampling model with finitely many types. A power-like distribution
Sub Stochastics and Decision Theory begr   +2 more
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Daniel Ellsberg and the Validation of Normative Propositions

open access: yesŒconomia, 2016
In the history of decision theory Daniel Ellsberg is known because his seminal paper “Risk, ambiguity and the Savage axioms” presented the counterexample to Bayesian decision-making that got the normative value of the theory into trouble.
Carlo Zappia
doaj   +1 more source

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