Results 71 to 80 of about 3,781,591 (289)
Rationality, Theory Acceptance and Decision Theory
Principia: An International Journal of Epistemology, 1998 Following Kuhn's main thesis according to which theory revision and acceptance is always paradigm relative, I propose to outline some possible consequences of such a view.
J. Nicolas Kaufmann
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Intertemporal consumption and lifecycle in a pandemic context: an experimental approximation
TendenciasThe Covid-19 pandemic generated uncertainty among consumers, a slowdown in consumption and an increase of the added saving at world level, the microeconomic evidence showed a tendency towards dissaving and growing consumption.
Claudia Milena Pico Bonilla +1 more
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Homeostatic reinforcement learning for integrating reward collection and physiological stability
eLife, 2014 Efficient regulation of internal homeostasis and defending it against perturbations requires adaptive behavioral strategies. However, the computational principles mediating the interaction between homeostatic and associative learning processes remain ...
Mehdi Keramati, Boris Gutkin
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Potential outcome and decision theoretic foundations for statistical causality
Journal of Causal Inference, 2023 In a recent work published in this journal, Philip Dawid has described a graphical causal model based on decision diagrams. This article describes how single-world intervention graphs (SWIGs) relate to these diagrams.
Richardson Thomas S., Robins James M.
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FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
A Unified Theory of Human Judgements and Decision-Making under Uncertainty
Entropy, 2020 Growing empirical evidence reveals that traditional set-theoretic structures cannot in general be applied to cognitive phenomena. This has raised several problems, as illustrated, for example, by probability judgement errors and decision-making (DM ...
Raffaele Pisano, Sandro Sozzo
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An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Anxiety, Avoidance, and Sequential Evaluation
Computational Psychiatry, 2020 Anxiety disorders are characterized by a range of aberrations in the processing of and response to threat, but there is little clarity what core pathogenesis might underlie these symptoms.
Samuel Zorowitz +2 more
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