Results 91 to 100 of about 3,781,591 (289)

Weakly Equivalent Arrays

open access: yes, 2014
The (extensional) theory of arrays is widely used to model systems. Hence, efficient decision procedures are needed to model check such systems. Current decision procedures for the theory of arrays saturate the read-over-write and extensionality axioms ...
H. Ganzinger   +5 more
core   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

THE NEW CIVIL PROCEDURE CODE AND THE NUDITY OF BALANCING

open access: yesRevista Eletrônica de Direito Processual, 2016
This article aims to examine in the ambit of decision theory the treating the new Code of Civil Procedure gave the exam of balancing in case of standards collision situation.
Denis Gleyce Pinto Moreira
doaj   +1 more source

A Theory of Regularized Markov Decision Processes

open access: yes, 2019
Many recent successful (deep) reinforcement learning algorithms make use of regularization, generally based on entropy or Kullback-Leibler divergence. We propose a general theory of regularized Markov Decision Processes that generalizes these approaches ...
Geist, Matthieu   +2 more
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Probabilistic Forecast for Real-Time Control of Rainwater Pollutant Loads in Urban Environments

open access: yesHydrology
Advanced wastewater management systems are necessary to effectively direct severely contaminated initial rainwater runoff to the treatment facility only when pollutant concentrations are elevated during the initial flush event, thereby reducing the risk ...
Annalaura Gabriele   +3 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Uncertainty-Aware Multimodal Fusion and Bayesian Decision-Making for DSS

open access: yesAppliedMath
Uncertainty-aware decision-making increasingly relies on multimodal sensing pipelines that must fuse correlated measurements, propagate uncertainty, and trigger reliable control actions. This study develops a unified mathematical framework for multimodal
Vesna Antoska Knights   +3 more
doaj   +1 more source

An Examination of the Volitional Stages in Consumer Decisions to Avoid Sweatshop Clothing [PDF]

open access: yes, 2006
While much research in ethical consumption has focused on contexts such as food, this research explores ethical consumer decision-making in the context of intention to avoid sweatshop clothing where consumer concern has increased but response from the ...
Bekin, C   +5 more
core  

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