Results 91 to 100 of about 8,382,503 (310)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
CAPACITY PLANNING OF URBAN ROADS IN CONDITION OF PASSENGERS’ TRAVEL MODE CHOICE
Вестник СибАДИ, 2018 Introduction. The authors conduct the research of the urban passenger transportation problem. Municipal authorities and passengers are regarded as participants of the passenger transportation system.
M. E. Koryagin, E. G. Timofeeva
doaj +1 more source
Information SciencesChristoph Jansen and Georg Schollmeyer contributed ...
C. Jansen +3 more
openaire +2 more sources
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Stochastic Recurrences and their Applications to the Analysis of Partition-Valued Processes [PDF]
, 2011 The thesis consists of two parts. In the first part (Chapter 1) a new technique is developed for the asymptotic analysis of the moments of linear random recurrences, and some general results are presented for the absorption times of non-increasing Markov
Sub Stochastics and Decision Theory begr +2 more
core
Coherent random permutations with biased record statistics [PDF]
, 2011 We consider random permutations that are defined coherently for all values of n, and for each n have a probability distribution which is conditionally uniform given the set of upper and lower record values.
Sub Stochastics and Decision Theory begr +4 more
core +2 more sources
A Rubinesque theory of decision
, 2004 Department of Philosophy technical ...
Kadane, J. B. +2 more
openaire +2 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source