Results 121 to 130 of about 4,714,659 (255)
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
"Law Reporting" in Europe in the Early-Modern Period: Two Experiences in Comparison [PDF]
, 2009 The article challenges the cliché handed down to us by the European legal tradition of a marked contrast between ‘common law’, assumed as case-law/anti-doctrinal law, always opposed to ‘civil law’, seen as doctrinal/non case-law.
FREDA, DOLORES
core +1 more source
Molecular Oncology, EarlyView.In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
wiley +1 more source
Nova Scientia, 2016 Introducción: La experiencia de los familiares que toman el rol de cuidadores primarios, en el proceso de una enfermedad terminal como el cáncer, proporciona información acerca de la toma de decisiones al final de la vida. El objetivo de este trabajo fue
Norma Alicia Ordóñez Vázquez +1 more
doaj +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Decisional Processes with Boolean Neural Network: the Emergence of Mental Schemes [PDF]
arXiv, 2010 Human decisional processes result from the employment of selected quantities of relevant information, generally synthesized from environmental incoming data and stored memories. Their main goal is the production of an appropriate and adaptive response to a cognitive or behavioral task.
arxiv
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
Molecular Oncology, EarlyView.The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source
Toma de decisiones en las organizaciones [PDF]
, 2013 En este escrito se abordará el tema toma de decisiones en las organizaciones, a través de cuatro funciones administrativas, que son: planeación, organización, dirección y control, factores importantes en los recursos humanos, monetarios propios y ajenos ...
Monterrosa Romero, Richard Nilso +1 more
core
Patterns to analyze requirements of a Decisional Information System [PDF]
arXiv, 2013 The domain of analysis and conception of Decisional Information System (DIS) is, highly, applying new techniques and methods to succeed the process of the decision and minimizing the time of conception. Our objective in this paper is to define a group of patterns to ensure a systematic reuse of our approach to analyse a DIS s business requirements.
arxiv
Molecular Oncology, EarlyView.A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul +11 more
wiley +1 more source