Results 81 to 90 of about 2,388,908 (340)

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Differences on Utilitarian and Moral Decision Between Male and Female

Pensamiento Psicológico, 2019
Objetivo. Los juicios morales se basan en decisiones que toman en cuenta la representación de las normas y la ley, los valores, la funcionalidad y la situación en sí.
César A. Acevedo-Triana, Juan Francisco Muñoz Olano, Pablo Reyes   +2 more
doaj   +1 more source

Finanzas Empresariales : Decisiones Financieras a Largo Plazo [PDF]

, 2017
Las decisiones financieras a largo plazo, se concentran en la construcción de los objetivos y metas de largo plazo, explicar el procedimiento y la teoría básica necesaria para tomar decisiones financieras a largo plazo, así como también las alternativas ...
Gonzáles Trujillo, Lester David, Sierra Mendoza, Daniel Josué   +1 more
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Variante del método promethee para decisiones multicriterio discretas

Costos y Gestión
Existen dos grandes divisiones en las situaciones de toma de decisiones con múltiples obje­tivos: programación multiobjetivo, referido a variables continuas, y decisiones multicriterio discretas. El trabajo se centra en la problemática de las decisiones
Raúl Alberto Ercole, Claudia Beatriz Peretto   +1 more
doaj   +1 more source

El liderazgo y su relación con la satisfacción de los clientes: un enfoque teórico

Innova Research Journal, 2018
En toda organización es importante que cada grupo tenga una estructura establecida, en donde siempre existirá quienes asuman un mayor grado de responsabilidad, evalúen, tomen decisiones y tengan su enfoque basado en los objetivos organizacionales.
Stefanie Desiré Villanueva Sampín, Osvaldo Santiago Carrera Soria, Maria Auxiliadora Guerrero Bejarano   +2 more
doaj   +1 more source

A Study on the Importance of Work Experience in Developing Entrepreneurial Vision, Confidence, Decision-Making Skills, Passion, and Motivation Among Final Year Students Taking Entrepreneurship Course

, 2021
Mohd Safwan Ghazali, Aw Yang, Teh Boon Teck, Yang Tay   +3 more
openalex   +2 more sources

Imágenes y proceso de toma de decisiones [PDF]

, 2005
Actas de las Terceras Jornadas Imagen, Cultura y Tecnología celebradas del 28 al 30 de julio de 2004 en la Universidad Carlos III de ...
Rodao, Florentino
core   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

PROSPECTIVE AND SCORECARD, A STRATEGIC WEAPON AGAINST ENVIRONMENTAL CHANGES

Anuario Facultad de Ciencias Económicas y Empresariales, 2016
Until the decade of the 70 the nucleus of the concern in companie´s bussiness management was constituted it the achievement of the efficiency, a very important economic condition, but with the turbulence of the environment this condition was necessary ...
María del C. Herrero-Infante, Yanet Mora-Herrero   +1 more
doaj