Results 111 to 120 of about 2,380,234 (309)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Why do farmers make non-profit decisions: investigating decisions made through drought
, 2010 There is a widespread belief that farmers only consider profit motives when making decisions. The literature recognises that profit-maximisation is not the sole influence on farmers' behaviour; however it does not explore the non-profit maximising ...
Loch, A.J., Bjornlund, H., Kuehne, G.
core
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Impact Evaluation of Merger Decisions [PDF]
This paper provides a comparative analysis of methods for the empirical ex post evaluation of merger control decisions. It develops a competition-policy oriented framework of assessment criteria for the leading evaluation methods and applies them to ...
Oliver Budzinski
core
Shaping women's reproductive decisions: the case of Georgia
, 2008 This article discusses decisions that women in Georgia make concerning their reproductive lives. Based on 26 in-depth interviews conducted in the urban and rural areas of Georgia, the research explores how women's reproductive experiences and decisions ...
Mariam Gagoshashvili
core +1 more source
Walking the talk: voluntary actions on marine protected areas on the high seas
npj Ocean SustainabilityConsensus-building in multilateral sectoral organizations can be crucial to the designation of marine protected areas (MPAs) on the high seas. While the consensus procedure can be abused to block collective decisions, the obligation-alone nature of MPAs ...
Jiliang Chen +2 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Food aid, scarce resources, and difficult decisions
, 1992 This article attempts to address the requirements of a methodology for evaluating food aid. It is an extension of an article by Fitzpatrick and Storey, which appeared in a recent issue of Development in Practice (Vol. 1, No. 3).
Watkins, Ben
core +1 more source