Results 111 to 120 of about 2,176,289 (311)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Flyer by Republicans for Responsible Decisions requesting donations and volunteers
This flyer or form letter from Republicans for Responsible Decisions includes an outline of the goals and platform of the organization and a partial list of the organization's leadership and ...
Republicans for Responsible Decisions
core
Decisions and dynamics: Unpacking the impact of contraceptive decisions on domestic violence [PDF]
Women’s empowerment in the form of intra-household bargaining power, employment, and education have been documented to both reduce and increase the prevalence of intimate partner violence (IPV).
Ojha, Manini, Babbar, Karan
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Choices and affective reactions to negative life events [PDF]
Judgment and Decision Making, 2008 Three experiments investigated individuals' preferences and affective reactions to negative life experiences. Participants had a more intense negative affective reaction when they were exposed to a highly negative life experience than when they were ...
John J. Seta +2 more
doaj
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Infectious Diseases and TherapyWe provide a taxonomy of the full health and societal value of maternal vaccination (MV) to prevent infant respiratory syncytial virus (RSV) disease. RSV is the leading cause of acute lower respiratory tract infections in infants and young children. Most
J. P. Sevilla +2 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Real options for adaptive decisions in primary industries [PDF]
, 2013 The long term sustainability of Australian crop and livestock farms is threatened with climate change and climate variability. In response, farmers may decide to (1) adjust practices and technologies, (2) change production systems, or (3) transform their
Greg Hertzler, Tim Capon, Todd Sanderson
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An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Walking the talk: voluntary actions on marine protected areas on the high seas
npj Ocean SustainabilityConsensus-building in multilateral sectoral organizations can be crucial to the designation of marine protected areas (MPAs) on the high seas. While the consensus procedure can be abused to block collective decisions, the obligation-alone nature of MPAs ...
Jiliang Chen +2 more
doaj +1 more source