Results 121 to 130 of about 2,976,561 (304)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
How do sustainability ideologies manifest in local planning decisions?
Sustainability underpins planning within the United Kingdom and is applied to all scales of development management decisions, ranging from small-scale householder planning applications to major urban regeneration schemes. Although sustainability has long
Bremner, L., Bachelor, D.
core +1 more source
Walking the talk: voluntary actions on marine protected areas on the high seas
npj Ocean SustainabilityConsensus-building in multilateral sectoral organizations can be crucial to the designation of marine protected areas (MPAs) on the high seas. While the consensus procedure can be abused to block collective decisions, the obligation-alone nature of MPAs ...
Jiliang Chen +2 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
WHICH ARE THE FACTORS INFLUENCING FINANCING DECISIONS IN SMEs? [PDF]
In this paper I review the literature in search of the factors that influence financing decisions in SMEs. Financial theories suggest that the only goal of a company is value maximization, but empirical studies have shown that small companies’ owners can
Flavia-Diana NISTOR
core
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Enhancing the Accessibility of Case Law: Leveraging Artificial Intelligence for the Retrieval of Court Decisions [PDF]
editorial reviewedAccess to court decisions is achieved through their publication in online or analogue formats. However, the publication of case law does not alone ensure its accessibility by lawyers and self-represented litigants seeking to formulate ...
TERZIDOU, Kalliopi
core
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source