Results 241 to 250 of about 2,380,234 (309)

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Legal Infoveillance of Unlicensed Medical Practices in South Korea Through Criminal Court Decisions Using Machine Learning: Retrospective Observational Study. [PDF]

JMIR Public Health Surveill
Kim MJ, Choi M.
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

An Eye-Tracking and Forecasting Experiment on Consumer Purchasing Decisions Through Product Reviews. [PDF]

J Eye Mov Res
Sarac SB, Atici KB, Bezci I, Dansuk AE, Yildirim FS.   +4 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Mechanisms to enhance the use of living evidence syntheses in health policy: Reflections from key informants globally. [PDF]

Health Res Policy Syst
Chakraborty S, Millard T, Kuchenmüller T, Green S, Synnot A, Mansilla C, Carter V, Turner T.   +7 more
europepmc   +1 more source

Empowering Patients: The Role of Shared Treatment Decision-Making in Advanced Bladder Cancer-A Podcast. [PDF]

Adv Ther
Kanesvaran R, Giannatempo P, Filicevas A.   +2 more
europepmc   +1 more source

Naming under constraint: gender, care and symbolic power in family life. [PDF]

Front Sociol
Albergaria-Almeida P.
europepmc   +1 more source

Ethical Dilemmas in End-of-Life Care: A Psychological and Anesthetic Perspective. [PDF]

Cureus
Nmezi J.
europepmc   +1 more source