Results 111 to 120 of about 90,677 (316)

Cluster Analysis of Extremely High Energy Cosmic Rays in the Northern Sky

, 1999
The arrival directions of extremely high energy cosmic rays (EHECR) above $4\times10^{19}$ eV, observed by four surface array experiments in the northern hemisphere,are examined for coincidences from similar directions in the sky.
A.A Watson, Al-Dargazelli, Chi, Efimov, Hayashida, J Lloyd-Evans, Kim, Landau, Lawrence, M Nagano, M Takeda, M Teshima, McBreen, Medina Tanco, Migdal, Shaver, Sigl, Stanev, Takeda, Y Uchihori   +19 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Testing of bent wire denture clasp metal's hardness and condition after titanium and zirconium nitride plasma spraying on its surface

RUDN Journal of Medicine, 2010
The durability comparative analysis of samples after different technologies of bent wire denture clasp treatment proved statistically significant declination of its density characteristics after titanium and zirconium nitride plasma spraying on its ...
E V Kuznetsova, V I Shemonaev, A S Stolyarchuk, A F Trudov   +3 more
doaj  

Smart Façades: Declination with the Electrochromic Glass

Challenging Glass Conference Proceedings, 2016
Energy saving and environmental protection don’t represent only a technical problem but also, and maybe most of all, an ethical problem. From this point of view, the Mediterranean area, characterized by a considerable Sunshine for at least 8 months a ...
G. Loddo, D. Ludoni
doaj   +1 more source

Proper Motions in the Andromeda Subgroup

, 2007
This article presents results of VLBI observations of regions of H2O maser activity in the Local Group galaxies M33 and IC10. Since all position measurements were made relative to extragalactic background sources, the proper motions of the two galaxies ...
A. Brunthaler, A. Brunthaler, A. Loeb, A.S. Kulessa, E. Corbelli, E.M. Wilcots, N.W. Evans, S. Piatek   +7 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A coverage independent method to analyze large scale anisotropies

, 2007
The arrival time distribution of cosmic ray events is well suited to extract information regarding sky anisotropies. For an experiment with nearly constant exposure, the frequency resolution one can achieve is given by the inverse of the time $T$ during ...
Antoine Letessier-Selvon, Aublin, de Jager, Fisher, Mollerach, Pierre Billoir, Rice, Sommers   +7 more
core   +3 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Investigating the Impact of Declination Angle on the Side Milling Process of Additively Manufactured Ti6Al4V Using a 3D Milling Finite Element Model

Engineering Proceedings
This study investigates the impact of declination angles (at 5, 10, and 15°) on the side milling process of additively manufactured Ti6Al4V. The finite element modelling (FEM) simulations are conducted using the Abaqus software and the Johnson–Cook (J-C)
Surinder Pal, Xavier Velay, Waqas Saleem
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source