Results 41 to 50 of about 40,967 (246)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Improved Object Detection with Content and Position Separation in Transformer

Remote Sensing
In object detection, Transformer-based models such as DETR have exhibited state-of-the-art performance, capitalizing on the attention mechanism to handle spatial relations and feature dependencies.
Yao Wang, Jong-Eun Ha
doaj   +1 more source

Performance evaluation of efficient combinational logic design using nanomaterial electronics

Cogent Engineering, 2017
Scaling down trend of CMOS transistor is approaching its lowest point, the rational substitute for the CMOS technology to attain advance improvements in terms of size, low power, and device density usage is an imperative essential.
Md. Abdullah-Al-Shafi, Ali Newaz Bahar, Firdous Ahmad, Kawsar Ahmed   +3 more
doaj   +1 more source

Neural-Network-Assisted Polar Code Decoding Schemes

Applied Sciences, 2022
The traditional fast successive-cancellation (SC) decoding algorithm can effectively reduce the decoding steps, but the decoding adopts a sub-optimal algorithm, so it cannot improve the bit error performance. In order to improve the bit error performance
Hengyan Liu, Limin Zhang, Wenjun Yan, Qing Ling   +3 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

SPADE: Superpixel Adjacency Driven Embedding for Three-Class Melanoma Segmentation

Algorithms
The accurate segmentation of pigmented skin lesions is a critical prerequisite for reliable melanoma detection, yet approximately 30% of lesions exhibit fuzzy or poorly defined borders.
Pablo Ordóñez, Ying Xie, Xinyue Zhang, Chloe Yixin Xie, Santiago Acosta, Issac Guitierrez   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Algorithmization and Hardware Implementation of Polar Coding for 5G Telecommunications

Transport and Telecommunication
The article explores a recursive algorithm for determining Bhattacharyya parameters, which is a measure of the degree of channel polarization for telecommunications with polar coding.
Pyatin Ilya, Boiko Juliy, Eromenko Oleksander   +2 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source