Results 121 to 130 of about 98,545 (284)

The future of clinical trials of gut microbiome therapeutics in cirrhosisKeypoints

JHEP Reports
Summary: The last two decades have witnessed an explosion of microbiome research, including in hepatology, with studies demonstrating altered microbial composition in liver disease.
Patricia P. Bloom, Raymond T. Chung
doaj   +1 more source

MiR‐145‐5p Attenuates Doxorubicin‐Induced Heart Injury Through Targeting Cardiomyocyte Pyroptosis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Doxorubicin (DOX), a potent anthracycline chemotherapeutic, exhibits dose‐dependent cardiotoxicity that limits its clinical utility. Although miR‐145‐5p demonstrates cardioprotective properties in cardiovascular diseases, its role in DOX‐induced cardiomyopathy remains undefined.
Xing‐Tao Chen, Yong‐Hong Yu, Yan‐Hua Du, Lin Xu, Xiang‐Ping Meng   +4 more
wiley   +1 more source

Admission Plasma Lipopolysaccharide‐binding protein, Procalcitonin, and Lactate for Early Identification of Nosocomial Infection in Cirrhotic Patients With Upper Gastrointestinal Bleeding: A Retrospective Analysis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study aimed to assess whether admission plasma lipopolysaccharide‐binding protein (LBP), procalcitonin (PCT), and lactate could improve detection of nosocomial infection in cirrhotic patients presenting with upper gastrointestinal bleeding (UGIB).
Li Chen, Shan‐Shan Dun, Fang Xiao
wiley   +1 more source

Role of Pediatric Otolaryngologist in Pediatric Tracheostomy Code Blue Cases: A New Safety Initiative

The Laryngoscope, EarlyView.
ABSTRACT Objective A “Code Blue” is a term to activate an alarm for the resuscitation team for a patient who has a cardiopulmonary arrest. The role of a pediatric otolaryngologist in a tracheostomy‐related code blue case is not clearly defined. We aim to describe the role of pediatric otolaryngologists in pediatric tracheostomy code blue (PTCB) cases ...
Deepa Shivnani, Miles Jonathan Klimara, M. S. Shruthi, Dnyanesh Balkrishna Amle, Matthew Ern Lin, Ian Kim, R. N. Ashwath Ram, Eswaran Venkat Raman, Gnanam Aram, Mallikarjun Ravi Kobal, Olivia E. Speed, Maie A. St. John, Dinesh Chhetri   +12 more
wiley   +1 more source

Vocal biomarkers in heart failure—design, rationale and baseline characteristics of the AHF-Voice study

Frontiers in Digital Health
Acute heart failure (AHF) is a life-threatening condition and a common cause of hospitalization. The defining clinical feature of AHF is volume overload, leading to pulmonary and peripheral edema and consequently to weight gain. Vocal biomarkers have the
Fabian Kerwagen, Fabian Kerwagen, Maximilian Bauser, Magdalena Baur, Fabian Kraus, Caroline Morbach, Caroline Morbach, Rüdiger Pryss, Kristen Rak, Stefan Frantz, Stefan Frantz, Michael Weber, Julia Hoxha, Stefan Störk, Stefan Störk   +14 more
doaj   +1 more source

The Adjunctive Efficacy of Fuzheng Huayu Tablet on Portal Hypertension with HBV Related Cirrhosis: A Protocol for a Multicenter Randomized Controlled Trial

Open Access Journal of Clinical Trials
Zhengxin Li,1 Yanan Guo,1,2 Jihan Huang,2 Jing Lv,1 Chenghai Liu1,3,4 1Department of Liver Disease, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, People’s Republic of China; 2Shanghai University of
Li Z, Guo Y, Huang J, Lv J, Liu C
doaj  

Attend and Diagnose: Clinical Time Series Analysis using Attention Models

, 2017
With widespread adoption of electronic health records, there is an increased emphasis for predictive models that can effectively deal with clinical time-series data.
Rajan, Deepta, Song, Huan, Spanias, Andreas, Thiagarajan, Jayaraman J.   +3 more
core   +1 more source

Multimodal Imaging Investigation of the Dentato‐Thalamo‐Cortical Pathway in Friedreich's Ataxia

Movement Disorders, EarlyView.
Abstract Background Friedreich's ataxia (FRDA) is a spinocerebellar neurodegenerative disorder. The dentato‐thalamo‐cortical (DTC) pathway, an important cerebellar output involved in motor control, plays a crucial role in the neural mechanisms underlying ataxia symptoms in FRDA.
Yinghua Jing, Imis Dogan, Ravi Dadsena, Jennifer Faber, Jörg B. Schulz, Kathrin Reetz, Sandro Romanzetti, on behalf of the FACROSS study group, Stella A. Lischewski, Kerstin Konrad, Miguel Pishnamaz, Maximillian Praster, Thomas Clavel, Vera Jankowski, Joachim Jankowski, Oliver Pabst, Katharina Marx‐Schütt, Nikolaus Marx, Julia Möllmann, Malte Jacobsen, Juergen Dukart, Simon Eickhoff, Ralf‐Dieter Hilgers   +22 more
wiley   +1 more source

Diagnosis and Management of Prenatal Hereditary Pyropoikilocytosis

Prenatal Diagnosis, EarlyView.
ABSTRACT Hereditary pyropoikilocytosis (HPP) is a severe hemolytic anemia caused by variants in SPTA1, SPTB, and EPB41. These weaken horizontal interactions in the erythrocyte cytoskeleton, causing membrane fragmentation and splenic sequestration. It will readily cause fetal anemia and often hydrops fetalis. Prenatal diagnosis requires first ruling out
Connor Hartzell, Samantha Stover, Nora Gibson, Timothy Olson, James Connelly, Matthew Grace, Jennifer Andrews   +6 more
wiley   +1 more source

Cerebral oxygenation and perfusion kinetics monitoring of military aircrew at high G using novel fNIRS wearable system

Frontiers in Neuroergonomics
IntroductionReal-time physiological episode (PE) detection and management in aircrew operating high-performance aircraft (HPA) is crucial for the US Military.
Thibault Roumengous, R. Casey Boutwell, Jason Strohmaier, Jared Allen, Brett Goldbach, Nicholas Marotta, Tanner Songkakul, Shelby Critcher, Bria G. Morse, Jeremy M. A. Beer, Paul M. Sherman   +10 more
doaj   +1 more source