Results 131 to 140 of about 98,545 (284)

The Use of Non‐Selective Beta‐Blockers in Cirrhotic Portal Hypertension

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
Non‐selective beta‐blockers (NSBBs) reduce portal pressure and play a key role in preventing variceal bleeding, managing ascites, and preventing hepatocellular carcinoma (HCC) in cirrhotic patients. Their clinical application requires individualized strategies and further optimization of indications. ABSTRACT Liver cirrhosis is the end stage of various
Tong Bu, Tianyuan Yang, Qi Wang
wiley   +1 more source

The Safety of Interferon‐Based Therapies in Chronic Hepatitis B Patients With Compensatory Cirrhosis

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
While nucleos(t)ide analog (Nuc) therapy is the standard for chronic hepatitis B, pegylated interferon‐alpha (Peg‐IFN‐α) provides unique advantages, including finite treatment duration and long‐term benefits. However, its use in patients with compensated cirrhosis remains limited due to persistent safety concerns about potential decompensation and ...
Qiran Zhang   +32 more
wiley   +1 more source

Spleen stiffness measurements during recompensation in patients with acutely decompensated liver cirrhosis: preliminary findings of a pilot study

open access: yesFrontiers in Medicine
BackgroundAcute decompensation (AD) in patients with liver cirrhosis is associated with a dramatic deterioration in prognosis. Immediate initiation of appropriate recompensation measures is essential to improve patient’s outcome, although objective ...
Dilan Elcin Bozal   +12 more
doaj   +1 more source

Chinese Registry on Transjugular Intrahepatic Portosystemic Shunts (CN‐TIPS): Protocol for a Registry‐Based, Prospective Prognostic Study

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
CN‐TIPS is a nationwide, multicenter prospective registry that will enroll 10,000 adults with portal hypertension undergoing transjugular intrahepatic portosystemic shunt in China, integrating perioperative clinical and hemodynamic metrics with standardized imaging (including computational modeling in a dedicated subcohort) and multi‐omics biospecimens,
Yi Xiang   +20 more
wiley   +1 more source

Physiological network approach to prognosis in cirrhosis: A shifting paradigm

open access: yesPhysiological Reports
Decompensated liver disease is complicated by multi‐organ failure and poor prognosis. The prognosis of patients with liver failure often dictates clinical management.
Tope Oyelade   +2 more
doaj   +1 more source

Cardiac disease in systemic sclerosis: Integrating pathobiology with clinical management

open access: yesRheumatology &Autoimmunity, EarlyView.
Abstract Systemic sclerosis (SSc) is a complex autoimmune disorder in which cardiovascular involvement remains a major determinant of morbidity and mortality. Cardiac injury in SSc results from the interplay of microvascular dysfunction, immune‐mediated inflammation, and progressive interstitial and replacement fibrosis, leading to myocardial disease ...
Henry Sutanto, Betty Rachma, Yuliasih
wiley   +1 more source

Is Hospital in the Home as safe and effective as inpatient care? [PDF]

open access: yes
When Activity-Based Funding (ABF) for public hospitals begins on 1 July this year, it should make it easier for hospitals to establish Hospital in the Home (HITH) services. The pricing framework underpinning the ABF system stipulates that public hospital
Anne-Marie Boxall, Gideon Caplan
core  

Content validation of the nursing diagnosis “Adult Disuse Syndrome”: A quantitative study

open access: yesInternational Journal of Nursing Knowledge, EarlyView.
Abstract Purpose This study aimed to establish the content validity of the proposed nursing diagnosis (ND) “Adult Disuse Syndrome” and all its components. Method This is an exploratory descriptive study of diagnostic content validation under Fehring's proposal.
Edinson Fabian Ardila‐Suárez   +2 more
wiley   +1 more source

Three Ventricular Assist Devices (True TriVAD) as Bridge to Durable Biventricular Support (BiVAD) in LVAD Patient With Severe Aortic Regurgitation

open access: yesArtificial Organs, EarlyView.
An LVAD patient with severe aortic regurgitation (AR) developed right heart failure and multi‐organ dysfunction (MOD). tRVAD support caused LV overload and pulmonary edema. Impella 5.5 implantation successfully unloaded the LV and stabilized the patient, enabling durable RVAD implantation with surgical aortic valve replacement.
Nikolaos Cholevas   +6 more
wiley   +1 more source

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