Results 31 to 40 of about 38,823 (268)

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Sensor-Reduced Active Power Decoupling Method for Single-Phase Rectifiers

Energies
Active power decoupling (APD) technology demonstrates significant advantages in addressing the mismatched second-order ripple power issue in single-phase rectifiers. However, conventional methods typically require additional voltage or current sensors to
Ming Chen, Shui Liu, Qinglong Cao, Hui Wang   +3 more
doaj   +1 more source

Adaptive Control of Flapping-Wing Micro Aerial Vehicle with Coupled Dynamics and Unknown Model Parameters

Applied Sciences, 2022
With the complex aerodynamics, the accurate system model of the flapping-wing micro aerial vehicle required for precise control is hard to acquire, meanwhile, due to the unique control strategy, the coupling between the actuators also brings a great ...
Jiawang Mou, Weiping Zhang, Chaofeng Wu, Qingcheng Guo   +3 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Generating Mechanism and Suppression of Impulse Voltage on Secondary Bus of Marine Electromagnetic Transmitter

Shanghai Jiaotong Daxue xuebao, 2023
Electromagnetic detection is the main method of marine oil and gas resources exploration, and marine electromagnetic transmitter is the key equipment of marine electromagnetic detection system.
TAO Haijun, DU Changshun, ZHANG Jinsheng, ZHENG Zheng
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Space and time joint optimization for vertical takeoff and landing aircraft in dense obstacles and interference environments

Systems Science & Control Engineering
The Vertical Takeoff and Landing Aircraft (VTOL) is capable of both low-speed hovering and high-speed flight. This paper proposes an autonomous motion planning and anti-wind disturbance control algorithm for the VTOL, implemented spatial and temporal ...
Liben Yang, Yu Li, Jianwen Tian, Dong Wang   +3 more
doaj   +1 more source

Dynamic Modeling, Simulation, and Experimental Verification of a Wafer Handling SCARA Robot With Decoupling Servo Control

IEEE Access, 2019
In this paper, we propose a novel coordinated control method based on decoupling servo control to design a 4-DOF direct-drive SCARA robot for wafer handling purpose.
Yunbo He, Xiquan Mai, Chengqiang Cui, Jian Gao, Zhijun Yang, Kai Zhang, Xun Chen, Yun Chen, Hui Tang   +8 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Adaptive Finite-Time Backstepping Integral Sliding Mode Control of Three-Degree-of-Freedom Stabilized System for Ship Propulsion-Assisted Sail Based on the Inverse System Method

Journal of Marine Science and Engineering
The three-degree-of-freedom (3-DOF) stabilized control system for ship propulsion-assisted sails is used to control the 3-DOF motion of sails to obtain offshore wind energy.
Sheng Liu, Jian Song, Lanyong Zhang, Yinchao Tan   +3 more
doaj   +1 more source