Results 231 to 240 of about 14,012 (309)

Social support for family caregivers of children and youth with special health care needs for home care: a scoping review. [PDF]

open access: yesRev Esc Enferm USP
Sulino-Gonçalves MC   +9 more
europepmc   +1 more source

PDIA6–SCD1 Axis Rewires Lipid Metabolism to Drive Gastric Cancer Progression

open access: yesAdvanced Science, EarlyView.
Protein disulfide isomerase A6 (PDIA6) is identified as an oncogenic driver in gastric cancer. PDIA6 directly binds and stabilizes SCD1 by limiting its ubiquitin–proteasome‐mediated degradation, thereby sustaining monounsaturated fatty acid (MUFA)‐enriched lipid homeostasis and lipid metabolic reprogramming.
Zhen Tian   +13 more
wiley   +1 more source

ProSiteHunter: A Unified Framework for Sequence‐Based Prediction of Protein‐Nucleic Acid and Protein‐Protein Binding Sites

open access: yesAdvanced Science, EarlyView.
This study proposed a unified sequence‐based framework for protein binding site prediction, which adopted a tri‐track semantic multi‐source feature fusion strategy to effectively capture diverse macromolecular interaction sites and further improved the accuracy of antibody‐antigen interaction prediction.
Dongliang Hou   +8 more
wiley   +1 more source

A Foundation Model Based CT Biomarker for Non‐Invasive Prediction of Response to Neoadjuvant Immunochemotherapy in Non‐Small Cell Lung Cancer

open access: yesAdvanced Science, EarlyView.
This study introduces a foundation model‐based biomarker for risk stratification of pathological response in non‐small cell lung cancer. A Vision Mamba super‐resolution model standardizes heterogeneous CT images. A multi‐task Swin Transformer then fine‐tunes a pre‐trained lung foundation model to jointly optimize tumor segmentation and response ...
Yanglan Xu   +10 more
wiley   +1 more source

Reconstruction of Nickel Chalcogenide Induced Ruthenium Nanoparticles Embedding for Oxygen Evolution: Mechanism Switching Enables Enhanced Catalytic Activity

open access: yesAdvanced Science, EarlyView.
Ru nanoparticles supported nickel chalcogens (Ru/NiX, X = S, Se), which enable fast electrooxidation to form an adaptively Ru embedding structure, featured by the compressed Ru─O─Ni bridge bonds at the Ru/NiOOH interface. On the one hand, Ru nanoparticles have a high affinity for capturing the OH−, consequently increasing the *O radical coverage.
Yuewen Wu   +10 more
wiley   +1 more source

Assessment of professionalism in undergraduate and graduate medical education: a scoping review. [PDF]

open access: yesBMC Med Educ
Jaramillo Villegas C   +3 more
europepmc   +1 more source

Dynamic Reconstruction‐Engineered Heterointerfaces for Acidic Hydrogen Evolution at Ampere‐Level Current Density

open access: yesAdvanced Science, EarlyView.
A dynamic reconstruction strategy was utilized to construct PtCu/Cu3P heterostructures on the surface of self‐supporting Cu3P nanowires. The loose porosity in the restructured layer, together with a dynamic “dissolution‐redeposition” equilibrium during electrocatalysis, enables the electrode to maintain a low, stable overpotential for 240 h at ampere ...
Kaixi Wang   +3 more
wiley   +1 more source

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