Results 161 to 170 of about 12,249 (194)

Mycobacterial α-glucans hijack dectin-1 to facilitate intracellular bacterial survival. [PDF]

Sci Immunol
Torigoe S, Salie S, Keeton R, Aylan B, Appelmelk BJ, Williams DL, Lowman DW, Sugiki T, Matsumoto S, Kawano A, Mizuno S, Matsuo K, Søndergaard JN, Wing JB, A Höft M, Shoesmith R, Ndengane M, Coussens AK, Willment JA, Gutierrez MG, Hoving JC, Yamasaki S, Brown GD.   +22 more
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Immune Responses to <i>Pneumocystis</i> in HIV-Infected and Non-HIV Immunocompromised Hosts. [PDF]

J Inflamm Res
Wang Y, Zheng C, Sun Y, Zhang Y.
europepmc   +1 more source

IL-6 regulates the polarization of Dectin-1 macrophages to weaken immune escape in thyroid cancer. [PDF]

J Transl Med
Deng X, Wu Y, Guo B, Ding Z, Fan Y, Wang J.   +5 more
europepmc   +1 more source

Dectin-2 Is a Direct Receptor for Mannose-Capped Lipoarabinomannan of Mycobacteria

Dectin-2 Is a Direct Receptor for Mannose-Capped Lipoarabinomannan of Mycobacteria
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Identification and gene expression of bovine C-type lectin dectin-2

Veterinary Immunology and Immunopathology, 2006
The C-type lectin receptor has been shown to recognize carbohydrate moieties of self and non-self antigens, thus serving as an innate immune receptor. Using bioinformatics and molecular cloning techniques, we isolated a bovine gene that encodes a polypeptide of 206 amino acids with structural features shared by mouse and human dectin-2, including a ...
M, Bonkobara, M, Hoshino, H, Yagihara, K, Tamura, M, Isotani, Y, Tanaka, T, Washizu, K, Ariizumi   +7 more
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Dectin-2 in Antimicrobial Immunity and Homeostasis

2016
Dendritic cell-associated lectin-2 (Dectin-2) is one of the most well-characterized members of the C-type lectin family. Recent studies have revealed its indispensable functions as a pattern recognition receptor (PRR) for a wide variety of pathogens, including fungi, bacteria, and viruses.
Rikio Yabe, Shinobu Saijo
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Induction of CD8+ T cell responses through targeting of antigen to Dectin-2

Cellular Immunology, 2006
Targeted delivery of antigens to dendritic cells (DC) can be used to optimise immunisation. We investigated whether the efficacy with which immune responses are induced can be improved by targeting Ags to a C-type lectin receptor, Dectin-2. When anti-Dectin-2 mAbs were injected s.c., mAb binding was detected on a low percentage of DC in the draining ...
Robert W, Carter, Clare, Thompson, Delyth M, Reid, Simon Y C, Wong, David F, Tough   +4 more
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Dendritic Cell Lectin Receptors (Dectin-2 Receptors Family)

2012
Dendritic cells (DCs) are special subsets of antigen presenting cells characterized by their potent capacity to activate immunologically naive T cells to induce initial immune responses. DCs are far more potent than macrophages and B cells in their capacity to activate immunologically naive T cells.
Rajesh K. Gupta, G. S. Gupta
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Dectin‐2‐mediated signaling triggered by the cell wall polysaccharides of Cryptococcus neoformans

Microbiology and Immunology, 2019
AbstractCryptococcus neoformans is rich in polysaccharides of the cell wall and capsule. Dectin‐2 recognizes high‐mannose polysaccharides and plays a central role in the immune response to fungal pathogens. Previously, we demonstrated Dectin‐2 was involved in the activation of dendritic cells upon stimulation with C.
Daiki Tanno, Rin Yokoyama, Kotone Kawamura, Yuki Kitai, Xiaoliang Yuan, Keiko Ishii, Magdia De Jesus, Hideki Yamamoto, Ko Sato, Tomomitsu Miyasaka, Hiroki Shimura, Nobuyuki Shibata, Yoshiyuki Adachi, Naohito Ohno, Sho Yamasaki, Kazuyoshi Kawakami   +15 more
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A6.16 Dectin-2 is essentially involved in innate immune response of experimental arthritis

Annals of the Rheumatic Diseases, 2015
Background C-type lectin receptors, like Toll-like receptors, belong to the pathogen pattern recognition family (PPR) and are essentially involved in immune responses against microbial infections. Dectin-2 (also known as Clec4n) is mainly expressed on myeloid cells and has been shown to interact with mannan ligands of candida albicans, mycobacteria ...
V Stögner, T Shvets, B Niederreiter, M Koenders, WB van den Berg, JS Smolen, K Redlich, S Hayer   +7 more
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