Results 41 to 50 of about 74,490 (295)
Frontiers in Psychology, 2022 This study examines whether psychological capital (PsyCap) indirectly predicts occupational well-being among Chinese special education teachers through work engagement.
Qiang Guo +6 more
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Psychometric properties of the UWES-S for South African university students
SA Journal of Industrial PsychologyOrientation: Student engagement is crucial for students’ success in higher education. Therefore, this study seeks to validate the psychometric properties of the Utrecht Work Engagement Scale-Student (UWES-S) version in a South African context.
Christiaan P. Brand +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
International Maritime Health, 2016 BACKGROUND A review of activities of Centro Internazionale Radio Medico (International Radio Medical Centre, CIRM) from its foundation in 1935 until its 80th anniversary in 2015 was accomplished. CIRM was founded in 1935 to provide medical assistance via
S. Mahdi, F. Amenta
semanticscholar +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
La dedicatoria de Cervantes «Al duque de Béjar»
Criticón, 2015 The dedication of the Quixote (1605) to the duke of Béjar is, as is known, for the greater part a plagiarism. There are some possibilities to explain it and not only the hypothesis that supposes that it was written by someone close to Robles after the ...
Ignacio Díez
doaj +1 more source
Public school teachers’ satisfaction with retention factors in relation to work engagement
SA Journal of Industrial Psychology, 2020 Orientation: The quality of education is influenced by the engagement, well-being, retention and performance of teachers. Literature shows that teachers are exiting the teaching profession at an alarming rate, and there are various and intertwined ...
Ronny Shibiti
doaj +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source