Results 31 to 40 of about 1,166,566 (281)

Resource dedication problem in a multi-project environment [PDF]

open access: yes, 2010
Resource dedication problem (RDP) in a multi-project environment is defined as the optimal dedication of resource capacities to dierent projects within the overall limits of the resources with the objective of minimizing the sum of the weighted ...
Besikci, Umut   +5 more
core   +5 more sources

La Sicilia descritta con medaglie de Filippo Paruta, deuxième édition dédiée par Leonardo Agostini à Gaston d’Orléans (1649)

open access: yesBulletin du Centre de Recherche du Château de Versailles, 2021
The first edition of Filippo Paruta’s La Sicilia descritta con medaglie (Palermo, 1612) was a bibliographical rarity which was in Mazarin’s library thanks to Cardinal Francesco Barberini.
Yvan Loskoutoff
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Gender and generation gaps in government organization: does it affect work engagement?

open access: yesJurnal Siasat Bisnis, 2021
Purpose: This research proposed to evaluate the differences between generations and gender work engagement. This evaluation is strategically needed to clarify the debate related to the issue of work engagement.
Gugup Kismono   +1 more
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Psychological Capital and Occupational Well-Being: Mediating Effects of Work Engagement Among Chinese Special Education Teachers

open access: yesFrontiers in Psychology, 2022
This study examines whether psychological capital (PsyCap) indirectly predicts occupational well-being among Chinese special education teachers through work engagement.
Qiang Guo   +6 more
doaj   +1 more source

This Humane Man of Letters [PDF]

open access: yes, 2006
A tribute to Marvin C.
Seidman, Barbara
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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