Results 31 to 40 of about 4,421 (165)

Retroperitoneal dedifferentiated liposarcoma with rare heterologous low-grade osteosarcoma: A case report

Radiology Case Reports
Dedifferentiated liposarcoma is a high-grade entity developed from a preexisting or recurrent well-differentiated liposarcoma, and rarely, it may contain divergent differentiation.
Chin-Yu Chiu, MD, Tzu-Ping Lin, MD, PhD, Jen-Fan Hang, MD, FIAC, Hsuen-En Huang, MD, Tzu-Hang Kao, MD, Shu-Huei Shen, MD   +5 more
doaj   +1 more source

Rare aggressive behavior of MDM2-amplified retroperitoneal dedifferentiated liposarcoma, with brain, lung and subcutaneous metastases

Rare Tumors, 2016
Dedifferentiated liposarcoma (DDL) is a histologically pleomorphic sarcoma, traditionally defined as well-differentiated liposarcoma with abrupt transition to high grade, nonlipogenic sarcoma.
Imen Ben Salha, Shane Zaidi, Jonathan Noujaim, Aisha B. Miah, Cyril Fisher, Robin L. Jones, Khin Thway   +6 more
doaj   +1 more source

Humanized immune system animal models and their recent applications

Animal Models and Experimental Medicine, EarlyView.
In this review, we provide an updated and comprehensive overview of the current state of humanized immune system animal model research. We discuss the variety of techniques used to produce humanized mice with their respective strengths and weaknesses, and evaluate the advantages and limitations of these models, including issues with incomplete immune ...
Nicolas Skuli, Rudra B. Amin, A’ishah Bakayoko, Marisa Kruidenier, Sahara Aqui, Sarah J. Skuli, Terence P. Gade   +6 more
wiley   +1 more source

Case report: a rare clinical presentation of a difficult diagnosis of dedifferentiated liposarcoma showing leiomyosarcoma phenotype in the ileocecal region

Frontiers in Oncology
Dedifferentiated liposarcoma is a malignant lipomatous tumor that rarely occurs in the gastrointestinal tract, including the ileocecal region. In this case, computed tomography and magnetic resonance imaging showed no fatty mass located in the mesenteric
Tomonori Kawasaki, Tomoaki Tashima, Kojiro Onohara, Yasumitsu Hirano, Misuzu Yamato, Suguru Shirotake, Tomoaki Torigoe, Yasuo Yazawa, Masataka Hirasaki, Masanori Wako, Taro Fujimaki, Jiro Ichikawa   +11 more
doaj   +1 more source

A case of dedifferentiated liposarcoma showing a biphasic pattern on 2-deoxy-2-F18- fluoro-D-glucose positron emission tomography/ computed tomography

Rare Tumors, 2013
Integrated 2-deoxy-2-F18-fluoro-D-glucose positron emission tomography combined with computed tomography (FDG-PET/CT) has been used in the field of soft tissue sarcoma.
Manabu Hoshi, Naoto Oebisu, Jun Takada, Hiroaki Nakamura, Kenichi Wakasa   +4 more
doaj   +1 more source

Surgical Management of Recurrent Retroperitoneal Sarcomas: Experience From a High‐Volume Sarcoma Centre

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background Retroperitoneal sarcoma (RPS) is a rare and complex malignancy, requiring specialized multidisciplinary care. While a significant progress has been made in managing a primary RPS, there is a limited literature on the outcomes of recurrent RPS (RecRPS).
Abdeali Saif Arif Kaderi, Tanvi M. Shah, Shraddha Patkar, Y. Aditya Sai Ram, Vinayaka S. Bairannavar, M. Myvizhi Kannan, Bharat Rekhi, Prabhat Bhargav, Kunal B. Gala, Afroj Bagwan, Mukta Ramadwar, Jifmi Jose, Nehal Khanna, Siddhartha Laskar, Mahesh Goel   +14 more
wiley   +1 more source

A Rare Case of Dedifferentiated Liposarcoma with Osteosarcomatous Differentiation-Diagnostic and Therapeutic Challenges

Diseases, 2023
Introduction: Liposarcomas are the most common of all sarcomas. A well-differentiated liposarcoma can transform into a dedifferentiated liposarcoma with myogenic, osteo- or chondrosarcomatous heterologous differentiation.
Patrycja Sosnowska-Sienkiewicz, Przemysław Mańkowski, Honorata Stadnik, Agata Dłubak, Anna Czekała, Marek Karczewski   +5 more
doaj   +1 more source

Urokinase Plasminogen Activator Receptor‐Associated Protein (uPARAP) as a Potential Next Generation Molecular Target for Treatment of Gastrointestinal Stromal Tumors (GIST)

International Journal of Cancer, Volume 159, Issue 3, Page 797-808, 1 August 2026.
A key component of the collagen internalization and lysosomal degradation cellular machinery, uPARAP may contribute to cancer progression. Here, the authors explored the expression of uPARAP in gastrointestinal stromal tumors using well‐annotated clinical patient samples and specimens from cell line‐ and patient‐derived xenografts.
Chao‐Chi Wang, Flavia Paternostro, Agnieszka Wozniak, Lore De Cock, Luna De Sutter, Kimberly Verbeeck, Ulla Vanleeuw, Daniël Gorgels, Che‐Jui Lee, Raf Sciot, Patrick Schöffski   +10 more
wiley   +1 more source

Dedifferentiated Liposarcoma Arising in an Esophageal Polyp: A Case Report

Case Reports in Gastrointestinal Medicine, 2012
Liposarcoma is one of the most common sarcomas in adults, but only rarely presents as an esophageal primary. There have been several reports of well-differentiated liposarcoma (WDL) arising in the esophagus, but we present a case of dedifferentiated ...
Jorge Torres-Mora, Ann Moyer, Mark Topazian, Jeffrey Alexander, Tsung-Teh Wu, Amber Seys, Karen Fritchie   +6 more
doaj   +1 more source

Clear cell renal carcinoma synchronous with dedifferentiated liposarcoma: a case report and review of the literature

Journal of Medical Case Reports, 2020
Background Multiple primary malignant neoplasms are not frequent but are increasing in incidence. Some of them are associated with genetic syndromes such as von Hippel-Lindau syndrome and Li-Fraumeni syndrome.
Estefania Beltran, Juan Esteban Garcia-Robledo, Lisa X. Rodríguez-Rojas, Martin Rengifo, Bladimir Perez, Harry Pachajoa, Angela R. Zambrano   +6 more
doaj   +1 more source